Aggressive osteoblastoma (AO) is a rare variant of osteoblastoma characterized histologically by epithelioid osteoblasts and clinically by local recurrences if not excised completely. Aggressive osteoblastoma has been described in various unusual sites; however, based on our search of the literature, involvement of the tarsal navicular has not been previously described. Herein, we report what we believe to be the first case of aggressive osteoblastoma involving the tarsal navicular in a 35-year-old woman. The tumor showed osteoid surrounded by epithelioid cells along with numerous osteoclastic giant cells. Absence of necrosis, mitosis, and infiltration into the surrounding native bone helped rule out the possibility of low-grade osteosarcoma.
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http://dx.doi.org/10.1053/j.jfas.2019.07.028 | DOI Listing |
Genes Chromosomes Cancer
November 2024
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Conventional high-grade osteosarcomas are characterized by aggressive radiologic features, cytologic pleomorphism, and complex genomics. However, rare examples of osteosarcomas remain challenging due to unusual histology, such as sclerosing or osteoblastoma-like features, which may require molecular confirmation of their complex genetic alterations. We have encountered such a case in a 17-year-old man, who presented with a third metatarsal sclerotic bone lesion, found incidentally in the work-up of a foot trauma.
View Article and Find Full Text PDFJ Neurosurg Case Lessons
November 2024
Department of Neurosurgery, The University of Texas Medical Branch at Galveston, Texas.
Background: Aneurysmal bone cysts (ABCs) are rare, benign, yet locally aggressive lesions that contain blood-filled channels that rarely occur in the thoracic spine of adults. The literature on the treatment of spinal ABCs is sparse, but the consensus is to achieve gross-total resection (GTR) due to these lesions being locally aggressive and to prevent recurrence.
Observations: This report describes a 35-year-old female admitted with back pain and right T5 dermatome radiculopathy without any inciting events.
J Craniomaxillofac Surg
January 2025
Division of Head and Neck Surgery, Department of Oral and Maxillofacial Surgery, University of Florida College of Medicine, Jacksonville, Florida, USA.
Surg Neurol Int
January 2024
Department of Neurosurgery, Kocaeli University, School of Medicine, Kocaeli, Turkey.
Background: Osteoblastomas, although rare, are benign primary bone tumors, with cervical spine involvement being exceptionally uncommon. Late diagnosis, especially in aggressive cases, can lead to surgical challenges. Oxidized regenerated cellulose (ORC) used for hemostasis may result in complications if left in the surgical field.
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