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http://dx.doi.org/10.1016/j.jaad.2020.06.1029 | DOI Listing |
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
Department of Chemistry, Isfahan University of Technology P. O. Box 84156-833111 Isfahan, Iran.
Heroin as a derivative of morphine contains the alkaloids and flavonoids with plenty of three to five aromatic rings. The latter is known as the main source of fluorescence emission after laser excitation. Here, laser induced fluorescence (LIF) spectroscopy at excitation line of 405 nm with the solvent densitometry method is introduced based on modified Beer-Lambert (MBL), for the rapid and reliable identification of street heroin samples.
View Article and Find Full Text PDFMicromachines (Basel)
December 2024
School of Opto-Electronical Engineering, Xi'an Technological University, Xi'an 710021, China.
The laser-induced damage threshold (LIDT) is a key measure of an optical component's resistance to laser damage, making its accurate determination crucial. Following the ISO 21254 standards, we studied the measurement strategy and uncertainty fitting method for laser damage, establishing a calculation model for uncertainty. Research indicates that precise LIDT measurement can be achieved by using a small energy level difference and conducting multiple measurements.
View Article and Find Full Text PDFFoods
January 2025
Department of Physics, University of Patras, 26504 Patras, Greece.
The fast detection of Extra Virgin Olive Oil (EVOO) adulteration with poorer quality and lower price vegetable oils is important for the protection of consumers and the market of olive oil from fraudulent activities, the latter exhibiting an increasing trend worldwide during the last few years. In this work, two optical spectroscopic techniques, namely, Laser-Induced Breakdown Spectroscopy (LIBS) and UV-Vis-NIR absorption spectroscopy, are employed and are assessed for EVOO adulteration detection, using the same set of olive oil samples. In total, 184 samples were studied, including 40 EVOOs and 144 binary mixtures with pomace, soybean, corn, and sunflower oils, at various concentrations (ranging from 10 to 90% /).
View Article and Find Full Text PDFJ Hazard Mater
January 2025
College of Engineering and Technology, Southwest University, Chongqing 400716, PR China. Electronic address:
The detection of heavy metals in soil is of great scientific significance for food security and human health. However, traditional detection methods are complicated, time-consuming, and labor-intensive. Herein, we developed a novel method using Au@SiO nanoparticles (NPs) and surface microstructure combined with laser-induced breakdown spectroscopy (Au@SiO NPs-SMS-LIBS) for the rapid detection of lead (Pb), chromium (Cr), and copper (Cu) in soil samples.
View Article and Find Full Text PDFMol Med
January 2025
Research Institute, National Cancer Center, Goyang-Si, Gyeonggi-Do, 10408, Republic of Korea.
Background: Double-strand breaks (DSBs) are primarily repaired through non-homologous end joining (NHEJ) and homologous recombination (HR). Given that DSBs are highly cytotoxic, PARP inhibitors (PARPi), a prominent class of anticancer drugs, are designed to target tumors with HR deficiency (HRD), such as those harboring BRCA mutations. However, many tumor cells acquire resistance to PARPi, often by restoring HR in HRD cells through the inactivation of NHEJ.
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