As a new-type of ultra-supercritical HI-IP rotor steel, X12CrMoWVNbN10-1-1 alloy steel has excellent integrative performance, which can effectively improve the power generation efficiency of the generator set. In this paper, uniaxial thermal compression tests were carried out over a temperature range of 950-1200 °C and strain rates of 0.05-5 s with a Gleeble-1500D thermal simulation testing machine. Moreover, based on hot compression experimental data and the theory of processing diagrams, in combination with the dynamic material model, a three-dimensional (3-D) thermal processing map considering the effect of strain was constructed. It was concluded that optimum thermal deformation conditions were as follows: the temperature range of 1150-1200 °C, the strain rate range of 0.05-0.634 s. Through secondary development of the finite element (FE) software FORGE, three-dimensional thermal processing map data were integrated into finite element software FORGE. The distributions of instability coefficient and power dissipation coefficient were obtained over various strain rates and temperatures of the Ø 8 × 12 mm cylinder specimen by using finite element simulation. It is shown that simulation results are consistent with the microstructure photos. The method proposed in this paper, which integrates the three-dimensional processing map into the finite element software FORGE (Forge NxT 2.1, Transvalor, Nice, France), can effectively predict the formability of X12CrMoWVNbN10-1-1 alloy steel.
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http://dx.doi.org/10.3390/ma13184118 | DOI Listing |
Nat Cell Biol
January 2025
Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.
Glioblastoma (GBM) is defined by heterogeneous and resilient cell populations that closely reflect neurodevelopmental cell types. Although it is clear that GBM echoes early and immature cell states, identifying the specific developmental programmes disrupted in these tumours has been hindered by a lack of high-resolution trajectories of glial and neuronal lineages. Here we delineate the course of human astrocyte maturation to uncover discrete developmental stages and attributes mirrored by GBM.
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January 2025
The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
The development of the human neocortex is highly dynamic, involving complex cellular trajectories controlled by gene regulation. Here we collected paired single-nucleus chromatin accessibility and transcriptome data from 38 human neocortical samples encompassing both the prefrontal cortex and the primary visual cortex. These samples span five main developmental stages, ranging from the first trimester to adolescence.
View Article and Find Full Text PDFSci Rep
January 2025
School of Mathematics and Computer, Wuhan Polytechnic University, Wuhan, 430048, China.
The rapid changes in the global environment have led to an unprecedented decline in biodiversity, with over 28% of species facing extinction. This includes snakes, which are key to ecological balance. Detecting snakes is challenging due to their camouflage and elusive nature, causing data loss and feature extraction difficulties in ecological monitoring.
View Article and Find Full Text PDFFood Res Int
January 2025
Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, 34469 Istanbul, Türkiye. Electronic address:
Lipid and protein oxidation have significant effects on the shelf-life and nutritional value of meat and meat products. While lipid oxidation has been extensively studied, it has been recognized that proteins are also susceptible to oxidation. However, the precise mechanisms of oxygen-induced amino acid and protein modifications in the food matrix remain unclear.
View Article and Find Full Text PDFFood Res Int
January 2025
Laboratory of Commodities and Territorial Analysis, Department of Economics and Law, University of Cassino and Southern Lazio, Via S. Angelo, Loc. Folcara, 03043 Cassino, (FR), Italy.
The potential use of edible insects as an alternative animal protein source has recently attracted a great deal of attention in Western countries. This is thanks to their numerous nutritional benefits, in particular in terms of vitamins and essential amino acids, and the need to guarantee food availability for the growing population. The aim of this scoping review is to analyse the current literature published in scientific journals regarding the main issues related to products containing edible insects, to map existing evidence and identify knowledge gaps.
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