Brassinosteroids (BRs) regulate a variety of physiological processes in plants via extensive crosstalk with diverse biological signaling networks. Although BRs are known to reciprocally regulate circadian oscillation, the molecular mechanism underlying BR-mediated regulation of circadian clock remains unknown. Here, we demonstrate that the BR-activated transcription factor -EMS-SUPPRESSOR 1 (BES1) integrates BR signaling into the circadian network in Arabidopsis. BES1 repressed expression of () and () at night by binding to their promoters, together with TOPLESS (TPL). The repression of and by BR treatment, which occurred during the night, was compromised in and mutants. Consistently, long-term treatment with BR shortened the circadian period, and BR-induced rhythmic shortening was impaired in and single mutants and in the double mutant. Overall, BR signaling is conveyed to the circadian oscillator via the BES1/TPL-CCA1/LHY module, contributing to gating diurnal BR responses in plants.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502351 | PMC |
| http://dx.doi.org/10.1016/j.isci.2020.101528 | DOI Listing |
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