We isolated 17 viral strains capable of causing cytopathic effects in mammalian cells and death in neonatal mice from sand flies in China. Phylogenetic analysis showed that these strains belonged to the genus Phlebovirus. These findings highlight the need to control this potentially emerging virus to help safeguard public health.
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http://dx.doi.org/10.3201/eid2610.191374 | DOI Listing |
Sci Rep
January 2025
Department of Civil and Environmental Engineering, Indian Institute of Technology Patna, Patna, Bihar, India.
Biochar has emerged as a promising soil amendment material, offering the potential to enhance mechanical and water retention properties. Geo-environmental structures constructed with biochar-amended soils (BAS) might experience a change in strength and water retention capacity due to extreme climactic changes, resulting in structural failures. The existing literature lacks a comprehensive study on the strength of BAS under prolonged curing, freeze-thaw cycles, and water retention behaviour for varying compaction conditions.
View Article and Find Full Text PDFMetabolites
December 2024
Nutrition and Health Program, Molecular Diagnostic Solutions Group, CSIRO Health & Biosecurity, Adelaide, SA 5000, Australia.
As the burden of Alzheimer's disease (AD) escalates with an ageing population, the demand for early and accessible diagnostic methods becomes increasingly urgent. Saliva, with its non-invasive and cost-effective nature, presents a promising alternative to cerebrospinal fluid and plasma for biomarker discovery. : In this study, we conducted a comprehensive multi-omics analysis of saliva samples ( = 20 mild cognitive impairment (MCI), = 20 Alzheimer's disease and age- and = 40 gender-matched cognitively normal individuals), from the South Australian Neurodegenerative Disease (SAND) cohort, integrating proteomics, metabolomics, and microbiome data with plasma measurements, including pTau181.
View Article and Find Full Text PDFEnviron Sci Process Impacts
December 2024
Anhui Bossco Environmental Protection Technology Co., Ltd, Ningguo, Anhui, 242301, China.
Contamination of heavy metals (HMs) has caused increasing concern due to their ecological toxicities and difficulties in degradation. The transport, retention, and release of HMs in porous media are highly related to their environmental fate and risk to groundwater. Column transport experiments and numerical simulations were conducted to investigate the retention and release behaviors of Cu, Pb, Cd, and Zn in the presence and absence of kaolin under varying ionic strengths and cation types.
View Article and Find Full Text PDFParasit Vectors
December 2024
Department of Parasitology, Faculty of Science, Charles University, Prague, Czech Republic.
Background: Leishmaniasis is a group of neglected vector-borne diseases transmitted by phlebotomine sand flies. Leishmania parasites must overcome various defenses in the sand fly midgut, including the insects's immune response. Insect immunity is regulated by the ecdysone hormone, which binds to its nuclear receptor (EcR) and activates the transcription of genes involved in insect immunity.
View Article and Find Full Text PDFParasit Vectors
December 2024
Center of Excellence in Vector Biology and Vector-Borne Diseases, Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Background: Leishmaniasis is an emerging vector-borne disease that occurs in Thailand. Although Leishmania (Mundinia) parasites, the causative agents of the disease have been identified, the vectors of the disease remain unidentified. In the present study, we collected sand flies from three caves located in endemic areas of leishmaniasis, including Lampang and Chiang Rai in northern Thailand, and Songkhla in southern Thailand.
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