In this paper, we demonstrate a novel non-invasive, wearable impedance sensor. The impedance sensor, using an impedance to frequency measurement, with two modes of resistance and capacitance measurement is implemented in CMOS 130 nm technology. The sensor consisting of current and voltage comparators for different mode of measurement, has a low power consumption of 30 μW per channel. The sensor is demonstrated in two applications, thoracic impedance and hand gesture recognition. Thoracic impedance is based on impedance modulation through fluid accumulation. Hand gestures are detected through tissue impedance sensing. The full thoracic impedance sensing system is smaller than a credit card, low cost, and consumes 3 mW which includes the sensor, transmitter, and power control unit. Data received by this sensor can be easily transferred for further processing and, eventually, detection of heart failure. The electrodes were implemented using conductive paint, and the system was validated using passive loads to represent human tissue models and test subjects. The hand gesture system operates on 600 μW with the maximum number of electrodes, and uses adhesive copper with electrical paint as electrodes.
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http://dx.doi.org/10.1109/TBCAS.2020.3025218 | DOI Listing |
Diagnostics (Basel)
December 2024
Referral Center for Pediatric Gastroenterology and Nutrition, Children's Hospital Zagreb, 10000 Zagreb, Croatia.
The relationship between symptoms of laryngopharyngeal reflux (LPR) and objective reflux measurements obtained through multichannel intraluminal impedance-pH (MII-pH) monitoring remains unclear. The aim of this study was to investigate the relationship between LPR symptoms and objective reflux episodes and possible associations between fibreoptic ENT findings, eosinophil counts, and serum IgE levels with reflux episodes detected by MII-pH. In this prospective study, MII-pH monitoring, fiberoptic laryngoscopy, nasal swabs for eosinophils, total serum IgE levels, and symptom assessment (Reflux Symptom Index, RSI) were performed in all children with suspected LPR.
View Article and Find Full Text PDFJ Clin Med
December 2024
University Hospital of Grenoble Alpes, INSERM U1300, 38043 Grenoble, France.
Cardiac implantable electronic devices and their integrated thoracic impedance sensors have been used to detect sleep apnea for over a decade now. Despite their usage in daily clinical practice, there are only limited data on their diagnostic accuracy. AIRLESS and UPGRADE were prospective investigator-driven trials meant to validate the AP scan (Boston Scientific, Marlborough, MA, USA) in heart failure cohorts.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Department of Cardiology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Cardiac implantable electronic devices (CIEDs) such as pacemakers and implantable cardioverter-defibrillators (ICDs) are increasingly used in the aging population. Modern CIEDs perform daily measurements, mainly aimed at discovering early signs of battery depletion or electrode dysfunction. Changes in thresholds, intracardiac signals, and pacing impedances can be caused by exacerbation of existing conditions or novel clinical problems.
View Article and Find Full Text PDFActa Biomater
December 2024
Division of Cardiac Surgery, Medical University of Graz, Austria.
This study aims to assess the outcomes of therapeutic options for aortic arch pathologies by comparing thoracic endovascular aortic repair (TEVAR) with open arch replacement (OAR) using woven polyester grafts from a mechanical and biomechanical perspective, with emphasis on ex vivo perfused human thoracic aortas reproducing heart rate and stroke volume conditions. Eleven non-diseased thoracic aortas from human cadavers were divided into TEVAR (n=5) and OAR (n=6) and tested using a custom-built mock circulation loop. Pressure, diameter, and stroke volume were monitored during perfusion before and after the intervention.
View Article and Find Full Text PDFThorac Cancer
December 2024
Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Background: Lung cancer is a pathology with an important incidence. It is a multifactorial disease characterized by epigenetic and nutritional factors. Indeed, there is a strong association between adipose tissue and the pulmonary system, and low-grade inflammation of obese and/or overweight subjects have a pivotal role in lung cancer establishment.
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