Association of Killer Cell Immunoglobulin-like Receptor and Human Leukocyte antigen-C Genotype with HLA-B27 Associated Acute Anterior Uveitis and Idiopathic Acute Anterior Uveitis in a Chinese Han Population.

Purpose: whether killer cell immunoglobulin-like receptors () and human leukocyte antigens C ) are associated with associated acute anterior uveitis (B27AAU) and idiopathic AAU (IAAU) remains unclear.

Methods: PCR with sequence-specific primers was used to analyze genes and alleles in a Chinese Han population of 196AAU patients and 210 control subjects.

Results: The higher frequencies of and (.009 and .044, respectively) and the lower frequencies of and (.034 and .009, respectively) were observed in B27AAU than control group. The higher frequencies of and (.009 and .044, respectively) and the lower frequencies of and (.000 and .001, respectively) were observed in IAAU than control group.

Conclusions: and , and might be susceptible for B27AAU and IAAU, respectively. and and might protect from B27AAU and IAAU, respectively.