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Creating a Health Utility Value for Birdshot Chorioretinopathy. | LitMetric

Creating a Health Utility Value for Birdshot Chorioretinopathy.

Ocul Immunol Inflamm

Academic Unit of Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.

Published: January 2022

AI Article Synopsis

  • The study aimed to establish a health utility value for birdshot chorioretinopathy (BCR) using Time Trade-Off (TTO) and Standard Gamble (SG) methods.
  • Researchers assessed 28 adult BCR patients through various questionnaires and clinical evaluations.
  • The findings revealed that a significant number of patients were willing to sacrifice years of life or accept a risk of death for the possibility of gaining perfect vision, highlighting the severe impact of BCR on their quality of life.

Article Abstract

Purpose: To create a health utility value for birdshot chorioretinopathy (BCR) using Time Trade-Off (TTO) and Standard Gamble (SG) utilities.

Method: Adult BCR patients completed TTO, SG, EQ-5D-5L, and NEI VFQ-25 questionnaires and underwent a detailed history and clinical examination.

Results: A total of 28 BCR patients (9 M, 19 F; mean age 62 years, range 47-83) were included. There were 22 patients with a logMAR vision of 0.3 or better in both eyes. Mean TTO was 0.90 ± SD 0.18 (range 0.33-1.0) and mean SG was 0.94 ± SD 0.14 (range 0.5-1.0). TTO correlated with EQ-5D-5L index value ( = .024) and NEI VFQ-25 composite score ( = .015).

Conclusions: Of 28 patients with BCR, 11 would trade remaining life (mean 5.4 years), and 6 would take a risk of immediate death (mean 28% risk), in return for perfect vision in both eyes for the rest of their life.

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Source
http://dx.doi.org/10.1080/09273948.2020.1799034DOI Listing

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