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A Pilot Study Evaluating the Feasibility and Efficacy of an In-Home Resonance-Based Electromagnetic Field Protection Device on Improving Markers of Health and Cognitive Function Among a Sample of Healthy Adults.
Integr Med (Encinitas)
September 2024
Altum Medical, San Jose, CA, United States.
Background: The dramatic increase in exposure to non-native sources of electromagnetic fields (EMF) in recent years has given rise to numerous human health concerns. The near pervasive exposure to radiofrequency (RF) emanating from wireless technologies inside the home (e.g.
View Article and Find Full Text PDFThe Mechanics of Building Functional Organs.
Cold Spring Harb Perspect Biol
June 2024
The Francis Crick Institute, London NW1 1AT, United Kingdom
Organ morphogenesis is multifaceted, multiscale, and fundamentally a robust process. Despite the complex and dynamic nature of embryonic development, organs are built with reproducible size, shape, and function, allowing them to support organismal growth and life. This striking reproducibility of tissue form exists because morphogenesis is not entirely hardwired.
View Article and Find Full Text PDFHardwiring tissue-specific AAV transduction in mice through engineered receptor expression.
Nat Methods
July 2023
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
Article Synopsis
- The development of transgenic mouse models has become easier with the introduction of a new system called SELECTIV, which efficiently expresses genes in specific cell types.
- This system uses adeno-associated virus (AAV) vectors combined with Cre-inducible overexpression of the AAV receptor (AAVR), significantly improving the transduction process in various cells, including muscle stem cells that normally resist AAV.
- SELECTIV also enhances specificity by using a whole-body knockout approach to remove the endogenous AAVR, offering better targeting in different tissues, which can lead to improved mouse models and gene delivery methods.
Cardiovascular Brain Circuits.
Circ Res
May 2023
Institute for Cardiovascular Prevention, Ludwig-Maximilians-University (LMU), Munich, Germany (S.K.M., C.Y., C.W., A.J.R.H.).
The cardiovascular system is hardwired to the brain via multilayered afferent and efferent polysynaptic axonal connections. Two major anatomically and functionally distinct though closely interacting subcircuits within the cardiovascular system have recently been defined: The artery-brain circuit and the heart-brain circuit. However, how the nervous system impacts cardiovascular disease progression remains poorly understood.
View Article and Find Full Text PDFEvaluation of a Multifaceted Protocol in Reducing Unnecessary Telemetry Monitoring across a Large Healthcare System.
South Med J
December 2022
From the Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Objectives: Telemetry is frequently overused in hospitals. The goal of this study was to evaluate a telemetry protocol aimed at decreasing inappropriate telemetry utilization across four different hospitals within a large healthcare system by modifying the electronic telemetry order to incorporate the 2017 American Heart Association practice guidelines on the appropriate use of telemetry and using an electronic nursing screening task form to safely discontinue telemetry.
Methods: We performed a retrospective analysis of telemetry utilization before and after we implemented a protocol across four hospitals within a large healthcare system.
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