Synthetic chlorins are not only fluorescent, the modulation of the tetrapyrrole system can also chelate metal ions. Conjugation of linkers at their pyrrolidines allows for conjugation to bio-molecules to create target specificity. By altering these chemo-photophysical properties, this work facilitates the use of chlorins in fluorescent imaging and positron emission tomography (PET).
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907923 | PMC |
http://dx.doi.org/10.1039/d0cc05494a | DOI Listing |
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