AI Article Synopsis
- BPA is an endocrine-disrupting chemical primarily used in making polycarbonate plastics, but concerns about its toxicity are leading to replacements like BPF and BPS in consumer products.
- A study analyzed urinary concentrations of BPA, BPF, and BPS in nearly 2,500 urine samples from Koreans collected between 2017 and 2018, revealing detection rates of 82.1% for BPA, 11.1% for BPF, and 63.6% for BPS.
- The study found that the daily intake of BPA was well below the established safety limits, marking it as the first of its kind to measure these bisphenols in a representative Korean population, enhancing understanding of exposure risks.
Article Abstract
Bisphenol A (BPA), an endocrine-disrupting chemical, has been used as a basic raw material for the production of polycarbonate plastics. As concern over the toxic effects of BPA grows, it is gradually being replaced in many consumer products with compounds such as bisphenol F (BPF) and bisphenol S (BPS). In this study, online solid-phase extraction-high-performance liquid chromatography-tandem mass spectrometry was used to analyze the urinary concentrations of BPA, BPF, and BPS in 2487 Korean urine samples collected between 2017 and 2018. The detection rates and geometric mean (GM) concentrations were as follows: BPA (82.1 %; 0.65 μg/L), BPF (11.1 %; not calculated), and BPS (63.6 %; 0.20 μg/L), respectively. The mean daily intake based on urinary BPA concentrations was 0.013 μg/kg bw/day (95th percentile, 0.089 μg/kg bw/day), which is lower than the tolerable daily intake. This is the first study observing urinary BPA, BPF, and BPS concentrations based on a nationally representative Korean population and could contribute to the evaluation of bisphenol analogue exposure levels in risk assessments.
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| http://dx.doi.org/10.1016/j.etap.2020.103491 | DOI Listing |
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