We describe an 84-year-old man presenting with a solitary, well-circumscribed, chronic erosion of the sole. Histopathologic examination confirmed diagnosis of circumscribed palmoplantar hypokeratosis. Circumscribed palmoplantar hypokeratosis is a rare and benign condition of unknown etiology presenting as an erosion on the palms or soles. Although lesions are typically asymptomatic, the entity is important for dermatologists and providers in other specialties to recognize, especially considering a differential diagnosis that includes neoplasia.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Aesthetic oral rehabilitation of the upper-anterior sector with supra-nano filling resin in a patient with woolly hair syndrome: case report.
Spec Care Dentist
July 2024
Faculty of Dentistry, Universidad Nacional Mayor de San Marcos, Lima, Peru.
Background: Woolly Hair Syndrome (WHS) is a rare birth condition that affects the structure of hair in non-black people. The pathogenesis is not yet defined. It is postulated that the hair follicle's desmosomes (specifically desmoplaquine, placoglobin and placofilin-1, which are cell structural proteins that keep the adhesion among close cells) would be altered in this pathology, leading to fragility in the cellular union.
View Article and Find Full Text PDFCircumscribed palmoplantar hypokeratosis.
Clin Dermatol
November 2021
Department of Dermatology, Ed. Herriot Hospital, Lyon, France. Electronic address:
Circumscribed palmoplantar hypokeratosis (CPH) is a rare acquired dermatosis first described in 2002. It affects mostly the thenar or hypothenar eminences of the palm of middle-aged or elderly women and manifests clinically with sharply limited, annular erythematous plaques with a depressed surface, rimmed by a slightly raised, keratotic border. Microscopically, circumscribed palmoplantar hypokeratosis shows a sharp decrease of the horny layer thickness, with few, if any, associated changes (parakeratosis, dermal inflammation).
View Article and Find Full Text PDFEffectiveness of a cosmetic device containing a combination of alpha- and beta-hydroxy acids, urea, and thuja for the treatment of seborrheic keratoses.
J Cosmet Dermatol
May 2022
Dermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Background: Seborrheic keratosis is a benign epidermal tumor of cosmetic concern-as it progressively increases in size, thickness, and pigmentation-on which topical treatments are poorly effective. Considering its keratotic component, effective products may include active principles with keratolytic action.
Aims: Evaluate the efficacy and tolerability of a topical cosmetic product with urea and hydroxy acids, in the treatment of seborrheic keratoses.
Circumscribed palmoplantar hypokeratosis: a case report and review of the literature.
Dermatol Online J
August 2020
Department of Dermatology, State University of New York Downstate, Brooklyn, NY.
We describe an 84-year-old man presenting with a solitary, well-circumscribed, chronic erosion of the sole. Histopathologic examination confirmed diagnosis of circumscribed palmoplantar hypokeratosis. Circumscribed palmoplantar hypokeratosis is a rare and benign condition of unknown etiology presenting as an erosion on the palms or soles.
View Article and Find Full Text PDFMalignant circumscribed acral hypokeratosis.
JAAD Case Rep
March 2020
Dermatopathology Partners of Knoxville, Knoxville, Tennessee.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!