AI Article Synopsis
- Two novel C terpenoids, perovsfolins A and B, were discovered from an Uzbek medicinal plant belonging to the Lamiaceae family.
- Their unique chemical structures feature a rare pentacyclic carbon skeleton with a C-C ester group, determined through advanced spectroscopic methods and computational analysis.
- Perovsfolin B showed potential anti-neuroinflammatory effects, suggesting possible medicinal applications.
Article Abstract
Structurally unique C terpenoids, perovsfolins A () and B (), were isolated from the aerial parts of an Uzbek medicinal plant, (Lamiaceae). Their chemical structures including an unprecedented 6/8/6/6/6 pentacyclic carbon skeleton with a C-C ester moiety were elucidated on the basis of spectroscopic analyses aided by density functional theory calculations as well as chemical evidence. Perovsfolin B () exhibited an anti-neuroinflammatory activity.
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| http://dx.doi.org/10.1021/acs.orglett.0c02855 | DOI Listing |
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