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Challenges in the diagnosis and management of dry tamponade.
Catheter Cardiovasc Interv
November 2024
Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA.
Dry tamponade is a rare complication of percutaneous coronary intervention. It encompasses a heterogenous pathophysiology and is used to describe hemodynamic compromise secondary to a coronary artery perforation, without free-flowing fluid in the pericardium. Tamponade physiology can result from compressive epicardial, intramyocardial, subepicardial hematomas, or dissecting intramyocardial hematomas.
View Article and Find Full Text PDFThe Application of Mesenchymal Stem Cells in Different Cardiovascular Disorders: Ways of Administration, and the Effectors.
Stem Cell Rev Rep
October 2024
Physiology, Department of Basic Medical Sciences, Medicine Faculty, Selcuk University, Konya, Türkiye.
The heart is an organ with a low ability to renew and repair itself. MSCs have cell surface markers such as CD45, CD34, CD31, CD4, CD11a, CD11b, CD15, CD18, CD25, CD49d, CD50, CD105, CD73, CD90, CD9, CD10, CD106, CD109, CD127, CD120a, CD120b, CD124, CD126, CD140a, CD140b, adherent properties and the ability to differentiate into cells such as adipocytes, osteoblasts and chondrocytes. Autogenic, allogeneic, normal, pretreated and genetically modified MSCs and secretomes are used in preclinical and clinical studies.
View Article and Find Full Text PDFEpicardial Adipose Tissue is Associated with Geometry Alteration and Diastolic Dysfunction in Prediabetic Cardiomyopathy.
J Clin Endocrinol Metab
June 2024
Division of Cardiology, Department of Internal Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan.
Background: Diastolic dysfunction and alterations in cardiac geometry are early indicators of diabetic cardiomyopathy. However, the association between cardiac changes across the glucose continuum and the contribution of epicardial adipose tissue (EAT) to these changes has not yet been investigated.
Purpose: In this study, we aim to investigated the EAT on cardiac diastolic function and structural alterations along the diabetic continuum using cardiac magnetic resonance imaging (CMRI).
Management of Intramyocardial Dissecting Hematoma Following Myocardial Infarction.
Turk Kardiyol Dern Ars
June 2024
Department of Cardiovascular Surgery, Istanbul Medipol University Hospital, Istanbul, Türkiye.
Intramyocardial dissecting hematoma (IDH) is a rare condition mostly seen following acute myocardial infarction, chest trauma, and cardiac surgery. It is described as an incomplete rupture caused by hemorrhagic dissection within the myocardium, rather than extending to the epicardial layer. Management strategies for IDH are controversial due to limited reports.
View Article and Find Full Text PDFVentricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms (VINTAGE): Deep Ablation in Inaccessible Targets.
JACC Clin Electrophysiol
May 2024
Cardiovascular Branch, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA. Electronic address:
Background: Deep intramural ventricular tachycardia substrate targets are difficult to access, map, and ablate from endocardial and epicardial surfaces, resulting in high recurrence rates.
Objectives: In this study, the authors introduce a novel approach called ventricular intramyocardial navigation for tachycardia ablation guided by electrograms (VINTAGE) to access and ablate anatomically challenging ventricular tachycardia from within the myocardium.
Methods: Guidewire/microcatheter combinations were navigated deep throughout the extravascular myocardium, accessed directly from the right ventricle cavity, in Yorkshire swine (6 naive, 1 infarcted).
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