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Tissue Eosinophils Threshold and its Association with Adult-Onset Asthma in Chronic Rhinosinusitis.
Int Forum Allergy Rhinol
January 2025
Center of Excellence in Otolaryngology-Head & Neck Surgery, Rajavithi Hospital, Bangkok, Thailand.
Introduction: Tissue eosinophil counts (TEC) might serve as a biomarker linking chronic rhinosinusitis (CRS) and the presence of adult-onset asthma. This study aimed to determine if TEC in sinus mucosa/polyps in CRS patients is an independent indicator of asthma and to identify its optimal cut-off point.
Methods: This cross-sectional study was conducted on primary CRS patients scheduled for surgery.
Clinical characteristics of IgG4-related retroperitoneal fibrosis in a cohort of 117 patients with idiopathic retroperitoneal fibrosis: a retrospective study.
Clin Rheumatol
January 2025
Department of Rheumatology and Immunology, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Objective: Retroperitoneal fibrosis (RPF) is a rare condition marked by inflammation and fibrosis affecting the peritoneal and retroperitoneal soft tissues. In recent years, the identification of IgG4-related diseases has brought to light a significant association with fibrous disorders, including RPF, which were once considered independent. In this comprehensive cohort study, we performed a comparative analysis of the demographic, clinical, laboratory, histopathological, and therapeutic characteristics between patients with IgG4-related RPF and those with idiopathic retroperitoneal fibrosis (iRPF).
View Article and Find Full Text PDFSolid pseudopapillary neoplasm of the pancreas in a 54-year-old woman: A case report and the literature analysis.
Pathol Res Pract
December 2024
Dnipro State Medical University, Dnipro 49044, Ukraine.
Introduction: Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor typically occurring in young females. This case presents an instance of SPN in a 54-year-old Caucasian female, highlighting atypical age of onset and providing new insights into the tumor's clinical and histopathological diversity.
Case Report: A 54-year-old female with no significant past medical history presented with upper abdominal discomfort and weakness.
Mechanistic modelling of allergen-induced airways disease in early life.
Sci Rep
January 2025
Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK.
Asthma affects approximately 300 million individuals worldwide and the onset predominantly arises in childhood. Children are exposed to multiple environmental irritants, such as viruses and allergens, that are common triggers for asthma onset, whilst their immune systems are developing in early life. Understanding the impact of allergen exposures on the developing immune system and resulting alterations in lung function in early life will help prevent the onset and progression of allergic asthma in children.
View Article and Find Full Text PDFInitial Magnetic Resonance Imaging Findings in Hepatic Fascioliasis and Serological and Radiological Response After Triclabendazole Treatment.
Am J Trop Med Hyg
December 2024
Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Article Synopsis
- Fascioliasis is a disease mainly found in livestock but has seen an increase in human cases in Korea, linked to a green vegetable juice delivery service.
- Patients diagnosed with fascioliasis often presented with specific symptoms like eosinophilia and were treated with triclabendazole, showing varying recovery patterns in liver abscesses over time.
- MRI findings indicated that late-diagnosed patients had a higher incidence of bile duct issues, while antibody levels and eosinophil counts significantly declined after treatment, suggesting the need for ongoing monitoring.
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