Genome-wide association study of bone quality and feed efficiency-related traits in Pekin ducks.

Genomics

National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics, Breeding and Reproduction, MARA; College of Animal Science and Technology, China Agricultural University, Beijing 100193, China. Electronic address:

Published: November 2020

Feeding and bone traits are vital for breeding and reproduction in the commercial duck industry. In this study, we performed a genome-wide association study for feeding and bone traits in a population of 540 lean-type Pekin ducks, followed by genotyping-by-sequencing procedures. The genetic parameters of feeding and bone traits were also estimated using genomic information. In total, seventy-eight significant SNPs were determined, and eleven of them reached the genome-wide significant level for 7 traits except for body weight at 42-day old. A peak of genome-wide significant SNPs was detected on chromosome 2 for feed conversion ratio (P-value = 7.46E-11), and the top SNP (P-value = 2.23E-08) for bone-breaking strength was also obtained in the upstream of gene RAPGEF5. This study provided a list of novel markers and candidate genes associated with feeding and bone traits in Pekin ducks, which could contribute to the genetic selection in duck breeding.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygeno.2020.09.023DOI Listing

Publication Analysis

Top Keywords

feeding bone
16
bone traits
16
pekin ducks
12
genome-wide association
8
association study
8
traits pekin
8
traits
6
bone
5
genome-wide
4
study
4

Similar Publications

Adaptive radiation, whereby a clade pairs rapid speciation with rapid phenotypic evolution, can result in an uneven distribution of biodiversity across the Metazoan tree. The cichlid fishes of East Africa have undergone multiple adaptive radiations within the major rift lakes. Cichlid radiations are marked by divergence across distinct habitat gradients producing many morphological and behavioural adaptations.

View Article and Find Full Text PDF
Article Synopsis
  • Obesity can lead to systemic inflammation and insulin resistance, increasing the risk of type 2 diabetes (T2D) and negatively impacting bone health, with unclear differences in effects between obesity and T2D.
  • The study aimed to investigate how hyperinsulinemic obesity and insulinopenic T2D affect bone structure and bone marrow adipose tissue (BMAT), while also exploring the relationship with CRAMP expression and levels.
  • Mice fed a high-fat diet exhibited significant weight gain and bone deterioration, while those with insulinopenic T2D showed severe glucose intolerance and less BMAT expansion, indicating differing impacts on bone health between the conditions.
View Article and Find Full Text PDF

Unlabelled: During the Iron Age, north-eastern Iberian communities relied on crop cultivation and animal husbandry for their subsistence. The latter was mainly focused on caprine, with sheep being prominent due to their suitability to the Mediterranean climate, orography, and environment. Despite the pivotal role of sheep in livestock husbandry, information on Iberian communities' feeding strategies for this species is limited.

View Article and Find Full Text PDF

Well-preserved specimens of a new species of arthrodiran placoderm, sp. nov. (Middle Devonian of Victoria, Australia), reveals previously unknown information on the dermal skeleton, body-shape and dentition of the wide-spread genus .

View Article and Find Full Text PDF

Characterisation of the influence of dietary fat and sugar on bone health utilising densitometry, micro-computed tomography and histomorphometry.

Bone

December 2024

Division of Clinical Anatomy, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University Tygerberg Campus, PO Box 241, Cape Town 8000, South Africa. Electronic address:

Obesogenic feeding can affect systemic metabolism and impact bone health and microarchitecture, but the findings of published studies often appear contradictory. This study aimed to compare the effects of a medium-fat/high-sugar (MF/HS) and a high-fat/high-fructose (HF/Fr) diet on the femora of weanling male Wistar rats, examining bone mineral content and density (BMC, BMD), cortical and cancellous bone microarchitecture and the cell populations within bone. Furthermore, we explored the correlations between circulating bone-targeting factors (in particular leptin, adiponectin and insulin) and bone parameters.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!