Gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) is a hepatocyte-specific, linear ionic contrast agent for MRI. In comparison to other linear contrast agents Gd-EOB-DTPA is excreted equally through liver and kidneys. This prospective longitudinal study investigates the signal intensity (SI) in the dentate nucleus (DN) on unenhanced T1-weighted images after repetitive application of Gd-EOB-DTPA. 46 patients were included into the study and 107 MRI examinations were performed. Statistical analysis of 25 patients showed no significant correlation between cumulative dose of Gd-EOB-DTPA and SI change and between the DN/Pons ratiolast and the mean DN/Pons ratiofirst. Subgroup analysis however revealed a significant correlation for one out of two readers. Gd-EOB-DTPA deposition could not be proven in the framework of this study.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3233/CH-209219 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Parabrachial CGRP neurons modulate active defensive behavior under a naturalistic threat.
Elife
January 2025
School of Psychology, Korea University, Seoul, Republic of Korea.
Recent studies suggest that calcitonin gene-related peptide (CGRP) neurons in the parabrachial nucleus (PBN) represent aversive information and signal a general alarm to the forebrain. If CGRP neurons serve as a true general alarm, their activation would modulate both passive nad active defensive behaviors depending on the magnitude and context of the threat. However, most prior research has focused on the role of CGRP neurons in passive freezing responses, with limited exploration of their involvement in active defensive behaviors.
View Article and Find Full Text PDFWe have employed a triazine-based conjugated polymer network (CPN) for the selective detection of hypochlorite in a semi-aqueous environment. CPNs have been widely employed in gas capture, separation, and adsorption, but the fluorescent properties of CPNs possessing extensive π-conjugated systems tend to be unexplored. Herein, we report the photophysical properties of the CPN and investigate its sensing capability towards hypochlorite.
View Article and Find Full Text PDFA computer vision model for the identification and scoring of calcium in aortic valve stenosis: a single-center experience.
Cardiovasc Diagn Ther
December 2024
East Slovak Institute of Cardiovascular Diseases and School of Medicine, Pavol Jozef Safarik University, Kosice, Slovakia.
Background: Echocardiography is widely used to assess aortic stenosis (AS) but can yield inconsistent results, leading to uncertainty about AS severity and the need for further diagnostics. This retrospective study aimed to evaluate a novel echocardiography-based marker, the signal intensity coefficient (SIC), for its potential in accurately identifying and quantifying calcium in AS, enhancing noninvasive diagnostic methods.
Methods: Between May 2022 and October 2023, 112 cases of AS that were previously considered severe by echocardiography were retrospectively evaluated, as well as a group of 50 cases of mild or moderate AS, both at the Eastern Slovak Institute of Cardiovascular Diseases in Kosice, Slovakia.
Assessing the preservation potential of successive hurricane overwash deposits in Florida, USA mangroves.
Sci Rep
January 2025
Department of Environmental Studies and Geology, Bryn Mawr College, Bryn Mawr, PA, USA.
Geologic records of tropical cyclones (TCs) in low-energy, back-barrier environments are established by identifying marine sediments via their allochthonous biogeochemical signal. These records have the potential to reconstruct TC intensity and frequency through time. However, modern analog studies are needed to understand which biogeochemical indicators of overwash sediments are best preserved and how post-depositional changes may affect their preservation.
View Article and Find Full Text PDFFiber-Optic Photoacoustic Gas Microprobe Based on Linear Spot-Type Multipass Cell.
Anal Chem
January 2025
School of Optoelectronic Engineering and Instrumentation Science, Dalian University of Technology, Dalian, Liaoning 116024, China.
A linear spot-type multipass cell-enhanced fiber-optic photoacoustic gas microprobe is proposed. To further reduce the volume of the gas chamber and enhance the photoacoustic signal, we designed the cross section of the photoacoustic tube as a slit with a height of 10 mm and a width of 1.5 mm.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!