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MicroRNA regulation of vascular function. | LitMetric

MicroRNA regulation of vascular function.

Vasc Biol

University/BHF Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

Published: June 2019

MicroRNAs (miRNAs) are small non-coding RNAs that orchestrate genetic networks by modulating gene expression. Given their importance in vascular development, homeostasis and diseases, along with the technical feasibility in deploying their function , the so-called 'vascular miRNAs' have become key targets for therapeutic intervention. Herein, we have summarised the state-of-the-art on vascular miRNAs and we have discussed the role miRNA biogenesis and the extracellular vesicles (EVs) miRNA transport in vascular biology.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439840PMC
http://dx.doi.org/10.1530/VB-19-0009DOI Listing

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