This study aims to screen bacterial isolates from Olabisi Onabanjo University Farmland for antibacterial activity against pathogenic microorganisms. Agar well diffusion method was used. Isolates were identified molecularly. Chi-square test revealed significant association between isolates, antibacterial activity with likelihood -value = 0.000 and 5% significant level. Six among thirty-five isolates exhibited antibacterial activity against the test pathogenic species. A greater antibacterial activity (50 % inhibition) was observed in strain PRE16. It inhibited the growth of and by 23.00 ± 2.00, 18.00 ± 2.00 and 20.00 ± 4.00 respectively. DNA sequencing revealed antagonist isolates as sp. BCN2, strain P30C4, strain KNUC205, strain KEM24 strain CSD05 and strain PRE16. Phylogenetic analysis revealed close relatedness of most isolates with species strains. These strains are suggested to be effective for the discovery of new antibacterial agents.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475235 | PMC |
http://dx.doi.org/10.1016/j.btre.2020.e00513 | DOI Listing |
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