Background: Recent evidence has shown that poor quality sleep is associated with depression, particularly among older individuals. Moreover, given that grandparent caregivers are more likely to report being depressed, it is crucial to identify whether poor sleep quality results in more depressive symptoms when older individuals are also caring for their grandchildren. Thus, the current study examined how caregiving status was associated with the relation between sleep quality and depressive symptoms and the further moderation of gender (ie, 3-way interaction).
Participants: The sample (N = 459, Mean age = 62.43, 58.40% female) was a subset of individuals recruited in the second wave of the MIDUS project completed in 2009.
Methods: Participants answered the Center for Epidemiological Studies Depression Scale (CESD), the Pittsburgh Sleep Quality Index (PSQI), and a question regarding grandparent caregiving status. Moderation analyses were conducted using AMOS 26.0.
Results: The interaction between global sleep quality and grandparent caregiving status was significant in predicting depressive symptoms, and the interactions examining global sleep quality, subjective sleep quality, sleep latency, sleep duration, sleep efficacy, sleep medication, and daytime dysfunction were significant for males when examined separately, whereby increased sleep difficulties were associated with more depressive symptoms. In all sleep domains, the slope of the interactions was sharper for grandparent caregivers, particularly for males.
Conclusion: Significant differences between interactions for males and females indicated 3-way interactions, such that interactions were significant for males and not females. Therefore, the relation of sleep on depressive symptoms was dependent on grandparent caregivers' status and gender.
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http://dx.doi.org/10.2147/NSS.S247568 | DOI Listing |
Intern Emerg Med
January 2025
Faculty of Medicine, Department of Emergency Medicine, Akdeniz University, Antalya, Turkey.
Patients presenting with suspected acute coronary syndrome (ACS) in the emergency department (ED) require rapid and accurate electrocardiographic (ECG) evaluation. This study aims to assess conventional ECG markers for diagnosing non-ST-elevation ACS (NSTE-ACS) in patients with chest discomfort and right bundle branch block (RBBB). A nested case-control design was employed to compare patients with RBBB admitted to the ED for suspected cardiac ischemia, focusing on those who developed NSTE-ACS versus those who did not.
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January 2025
Department of Neurology, The Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Guangxi, China.
Benign paroxysmal vertigo (BPV) is a common cause of dizziness, and some patients are comorbid with psychiatric disorders such as depression, requiring intervention with antidepressants. However, the causal association between BPV, depression and antidepressants has not been clearly established. We used two-sample bidirectional Mendelian randomization (MR) to analyze the causal association between BPV, depression, and antidepressants.
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January 2025
School of Medicine, Trinity College Dublin, Dublin, Ireland.
Purpose: As the global population of older adults rises, the United Nations Decade of Healthy Ageing (2021-2030) advocates for disease prevention, management, and enhancing overall wellbeing in older adults. We reviewed the MEDLINE literature under the MeSH term "music therapy" (MT), for its role in promoting healthy ageing.
Methods: A systematic search of the MEDLINE biomedical database (Ovid) was conducted using "MT" and "Ageing" as keywords, retrieving relevant full-text studies in English.
Sci Rep
January 2025
Institute of Brain Diseases and Cognition, School of Medicine, Xiamen University, Xiamen, 361102, Fujian, China.
Altitude training has been widely adopted. This study aimed to establish a mice model to determine the time point for achieving the best endurance at the lowland. C57BL/6 and BALB/c male mice were used to establish a mice model of hypoxic training with normoxic training mice, hypoxic mice, and normoxic mice as controls.
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January 2025
Faculty of Computer Science and Engineering, Shahid Beheshti University, Tehran, Iran.
Genetics plays a significant role in Multiple Sclerosis (MS), with approximately 12.6% of cases occurring in familial form. While previous studies have demonstrated differences in disease progression and MRI findings between familial and sporadic MS, there has been no comparison of cognitive impairment between them.
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