From ACE to ACENO: How America's Munson added Harley's British mixture to nitrous oxide.

J Anesth Hist

Anesthesiology and Perioperative Medicine, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106, USA; Oral and Maxillofacial Surgery, Case Western Reserve University School of Dental Medicine, 2124 Cornell Road, Cleveland, OH 44106, USA; Wood Library-Museum of Anesthesiology, American Society of Anesthesiologists, 1061 American Lane, Schaumburg, IL 60173-4973, USA. Electronic address:

Published: September 2020

An Ohio dentist, Corydon Munson, patented a gasometer with an attachment for vaporizing trace amounts of volatile general anesthetics or their mixtures into unoxygenated nitrous oxide. After vaporizing a variant of George Harley's ACE mixture into nitrous oxide, Munson branded his own novel anesthetic combination as ACENO.

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Source
http://dx.doi.org/10.1016/j.janh.2020.07.006DOI Listing

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