AI Article Synopsis
- - The study investigates how common Pseudomonas aeruginosa, a harmful bacteria, is among Cystic Fibrosis patients in Iran, analyzing 14 articles up to July 2019 using various scientific databases.
- - The findings reveal that the overall prevalence of P. aeruginosa in these patients is 40.6%, with significant variation across different studies.
- - The researchers emphasize the need for further investigation into the risk factors and transmission of P. aeruginosa due to its serious health impacts on Cystic Fibrosis patients.
Article Abstract
The present study aims to investigate the prevalence of Pseudomonas aeruginosa in Iranian Cystic Fibrosis (CF) patients. We conducted a systematic search on this topic in Web of Science, PubMed, Embase, Scopus, and Google Scholar electronic databases to the end of July 2019. Then, 14 articles with eligible criteria were selected for data extraction and analysis by Comprehensive Meta-Analysis Software. The pooled prevalence of P. aeruginosa was 40.6% (95% CI: 32.4%-49.4%) ranging from 32.4% to 49.4%. There was a significant heterogeneity among the studies (χ2 =21.02; p <0.001; I2 = 86.07%). The funnel plot for publication bias showed no evidence of asymmetry. Based on the results of Begg's and Egger's test no significant publication bias was observed. The study demonstrated a relative prevalence of P. aeruginosa among CF patients in Iran. Due to the rapid spread and infection severity of P. aeruginosa and other opportunistic pathogens, efforts are required to identify risk factors, reservoirs, transmission routes and source of infection.
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