This article has been withdrawn at the request of the editor. The Publisher apologizes for any inconvenience this may cause.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.envres.2020.110168 | DOI Listing |
Environ Res
May 2021
Environmental Health Laboratory, Department of Environmental Sciences, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
This article has been withdrawn at the request of the editor. The Publisher apologizes for any inconvenience this may cause.
View Article and Find Full Text PDFNeurosci Lett
September 2010
Department of Psychology, Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40536-0356, USA.
Acute and prolonged methamphetamine (METH) exposure has been reported to moderate the function of N-methyl-d-aspartate type glutamate receptors (NMDAr) in the hippocampus. These effects have been found to be associated with enhanced NMDAr-dependent release of Ca(2+) from IP(3)-sensitive intracellular stores. The present studies were designed to extend these findings and examine the role of the endoplasmic membrane (ER) bound orphan receptor, the sigma-1 receptor, in NMDA-induced neuronal injury and METH withdrawal-potentiated NMDA-induced neuronal injury.
View Article and Find Full Text PDFAlcohol Clin Exp Res
July 2008
Department of Psychology, University of Kentucky, Lexington, Kentucky 40536-0509, USA.
Background: Neuronal adaptations that occur during chronic ethanol (EtOH) exposure have been observed to sensitize the brain to excitotoxic insult during withdrawal. The adenosine receptor system warrants further examination in this regard, as recent evidence has implicated adenosine receptor involvement in the behavioral effects of both EtOH exposure and withdrawal.
Methods: The current studies examined effects of adenosine A(1) receptor manipulation on neuronal injury in EtOH-naive and EtOH-withdrawn male and female rat hippocampal slice cultures.
Alcohol Clin Exp Res
June 2008
Psychology Department, University of Kentucky, Lexington, Kentucky 40506-0044, USA.
Background: Polyamines are synthesized and released in high concentrations during CNS development. These agents can potentiate N-methyl-D-aspartate receptor (NMDAR) function and appear to play an important role in CNS development. Previous work has shown that polyamine release is increased during ethanol withdrawal (EWD).
View Article and Find Full Text PDFAnaesth Intensive Care
August 1991
Department of Anaesthesia and Intensive Care, University of Adelaide, South Australia.
Carbon monoxide (CO) 1% was administered to anaesthetised rabbits for 15 minutes. Despite a 28% +/- 5.8 (SEM) fall in mean arterial blood pressure during the CO exposure, cerebral blood flow increased by 236% +/- 36.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!