AI Article Synopsis
- Candida nivariensis is a little-known fungus, part of the Candida glabrata complex, first identified in 2005 using DNA sequencing.* -
- A case of deep-seated infection from this fungus occurred in a 77-year-old man after prostate surgery, with initial tests misidentifying it as C. glabrata.* -
- Accurate identification was achieved through MALDI-TOF mass spectrometry, which proved effective, especially since the isolate was resistant to fluconazole, similar to around 20% of cases.*
Article Abstract
Candida nivariensis is a cryptic fungal species classified within the Candida glabrata complex. It was described for the first time in 2005 by the means of DNA sequencing. We report a rare case of C. nivariensis deep-seated infection occurring in a 77-year-old man hospitalized for cysto-prostatectomy. Phenotypic testing based on the direct examination and the macroscopic features of the in vitro culture initially suggested C. glabrata species, while MALDI-TOF mass spectrometry enables correct identification. The isolate was found resistant to fluconazole, like in almost 20% of the reported cases. Herein, we present our practical strategy to reliably characterize this rare cryptic species. To date, MALDI-TOF mass spectrometry-based analysis showed very good results for such a purpose.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.mycmed.2020.101042 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!