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http://dx.doi.org/10.12788/cutis.0062DOI Listing

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Article Synopsis
  • Generalized morphea and eosinophilic fasciitis (EF) are rare skin diseases that cause skin thickening and sclerotic changes, and their overlap leads to worse patient outcomes.
  • A case report detailed a 36-year-old man who rapidly developed these conditions following severe burn injuries from a gasoline explosion, displaying symptoms like skin contractures and tenderness.
  • The patient showed limited response to various treatments, emphasizing the need for early recognition and proactive management strategies for individuals at risk of this overlap syndrome.
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Background: Ligneous periodontitis is a rare periodontal condition characterized by pseudomembranous enlargement of gingiva with marked impairment in fibrinolysis. The term ligneous is defined as made of, consisting of, or resembling wood; woody. Few cases of ligneous disease have been described in the literature.

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Morphea is a rare skin condition characterized by erythematous or violaceous lesions as well as sclerotic plaques. Patients with morphea frequently have other autoimmune disorders. Contributing factors are thought to be autoimmunity and an increase in extracellular matrix production.

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The cutaneous manifestations of Crohn disease (CD) are varied and include pyoderma gangrenosum, erythema nodosum, and metastatic CD (MCD). The latter is defined as the occurrence of granulomatous lesions at a skin site distant from the gastrointestinal tract. Metastatic CD involving the vulva and perineum is rare and thus often is difficult to diagnose.

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