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Role of vascularised fibula graft in the surgical management of radiation-induced midshaft femoral fractures. Case report and literature review.
World J Surg Oncol
December 2024
Department of Orthopaedic Surgery, Sarcoma Unit, St Vincent's Hospital Melbourne, 41 Victoria Parade, Fitzroy, VIC, 3065, Australia.
Background: Post-radiation fractures (PRF) are a recognised complication of radiation treatment for soft tissue sarcomas. They have a low incidence and typically occur up to 5 years following treatment, more commonly affecting the pelvis, ribs and femur. Due to radiation-induced changes in bone, PRFs typically require more complicated intervention compared to post-trauma fractures, however, limited literature exists, particularly in regards to mid-shaft femoral PRFs.
View Article and Find Full Text PDFAn MDS Patient with Deletion 20q and a t(9;22)(q34;q11.2): A Case Report and Review of the Literature.
J Assoc Genet Technol
January 2024
The International Circle of Genetics Studies, Stony Brook Chapter, NY.
We report a 76-year-old male patient with myelodysplastic syndrome (MDS) with a t(9;22) and deletion 20q only by FISH. Past medical history is significant for prostate cancer status post radiation therapy and a 28-pack-year smoking history. In 2016, the patient developed a DVT and incidentally was found to have a BCR::ABL1 (p210) by PCR analysis (level of 0.
View Article and Find Full Text PDFThe initial implementation of the transverse bone transport technique in the post-radiation region of the mandible. A pre-clinical in vivo study.
BMC Oral Health
November 2024
College & Hospital of Stomatology, Guangxi Medical University, No.10 Shuangyong Road, Nanning, Guangxi, 530021, P.R. China.
Background: To link the treatment of radiation injury with angiogenesis, and to design and seek a new therapeutic technique for the prevention and treatment of radiation injury.
Methods: The transverse bone transport device for rabbit mandible was designed and manufactured. Eighteen New Zealand white rabbits were randomly divided into a radiotherapy group and a normal group.
A prospective study of changes in bone health in adult cancer patients treated with pelvic radiotherapy.
Rep Pract Oncol Radiother
March 2024
Department of Radiotherapy, Institute of Postgraduate Medical Education and Research, Kolkata, India.
Article Synopsis
- Cancer treatment often involves pelvic radiation therapy, which can impact bone health, particularly in terms of bone mineral density and blood parameters.
- This study examined changes in bone health indicators, including Z scores and alkaline phosphatase levels, in patients with pelvic malignancies over a six-month period post-treatment.
- Results indicated a significant decrease in Z scores and an increase in serum alkaline phosphatase three months after radiation therapy, highlighting a peak in bone turnover during this time.
Pubic bone osteomyelitis and fistulas after radiation therapy of the pelvic region: patient-reported outcomes and urological management of a rare but serious complication.
World J Urol
August 2024
Department of Urology and Urologic Surgery, University Medical Centre Mannheim (UMM), University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Purpose: This study investigated late urinary adverse events (UAEs) in patients who underwent pelvic radiation therapy, with a focus on occurrence, diagnostic characteristics and the impact of subsequent extirpative surgery with the need of urinary diversion on quality of life.
Methods: A retrospective analysis of 20 patients after pelvic radiotherapy (2016-2022) was conducted. Data included demographics, perioperative details, oncological parameters, and patient-reported outcomes.
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