The addition of a weak oscillating field modifying strongly dressed spins enhances and enriches the system quantum dynamics. Through low-order harmonic mixing, the bichromatic driving generates additional rectified static field acting on the spin system. The secondary field allows for a fine tuning of the atomic response and produces effects not accessible with a single dressing field, such as a spatial triaxial anisotropy of the spin coupling constants and acceleration of the spin dynamics. This tuning-dressed configuration introduces an extra handle for the system full engineering in quantum control applications. Tuning amplitude, harmonic content, spatial orientation, and phase relation are control parameters. A theoretical analysis, based on perturbative approach, is experimentally tested by applying a bichromatic radiofrequency field to an optically pumped Cs atomic vapour. The theoretical predictions are precisely confirmed by measurements performed with tuning frequencies up to the third harmonic.
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http://dx.doi.org/10.1103/PhysRevLett.125.093203 | DOI Listing |
J Am Med Inform Assoc
December 2024
Department of Radiology, Stanford University, Stanford, CA 94304, United States.
Objective: Brief hospital course (BHC) summaries are clinical documents that summarize a patient's hospital stay. While large language models (LLMs) depict remarkable capabilities in automating real-world tasks, their capabilities for healthcare applications such as synthesizing BHCs from clinical notes have not been shown. We introduce a novel preprocessed dataset, the MIMIC-IV-BHC, encapsulating clinical note and BHC pairs to adapt LLMs for BHC synthesis.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
School of Biomedical Engineering, ShanghaiTech University, Shanghai, China.
Background: About 50-90% people with dementia would develop behavioral disturbances, namely, behavioral and psychological symptoms of dementia (BPSD). Antipsychotic medications are widely used to control severe BPSD symptoms which suffers serious safety risks. It is challenge for individualized precise prediction of antipsychotic drug doses.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Centre for Brain Research (CBR), Indian Institute of Science, Bengaluru, Karnataka, India.
Background: Alzheimer's disease is a progressive neurodegenerative disorder that mainly affects the brain resulting gradual decline in a cognitive function, memory impairment, alterations in behavior, potentially resulting in the inability to engage in a conversation and react to the surroundings. Corpus callosum (CC) is the principal white fabric matter present in the center of the brain that connects the left and right cerebral hemispheres. Neurodegenerative diseases can impact the size and structure of the CC, leading to its atrophy and dysfunction.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, Scotland, UK.
Background: To date, all computerised perivascular spaces (PVS) quantification methods require case-wise, imaging modality, or study-specific parameter adjustments, and suffer from generalisability problems in clinical settings, and misdetection of other cerebral small vessel disease (CSVD) markers. We propose a deep learning-based PVS detection method to overcome these issues. We compare our proposal on magnetic resonance imaging data of CSVD participants against the performance of the Frangi filter.
View Article and Find Full Text PDFBackground: The HEAD study aims to collect a large dataset of multiple tau-PET tracers to provide robust anchor values for tau-PET harmonization. Here, we tested the hypothesis that anchoring two tau tracer uptake values using head-to-head measurements has the potential to generate an accurate universal tau-PET scale, named Uniτ(tau).
Methods: We assessed 200 individuals across the aging and AD spectrum (Training: HEAD data freeze 2.
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