AI Article Synopsis
- Much of the science behind the global response to COVID-19 relates to soft matter, specifically the structure of coronaviruses and their transmission routes.
- Coronaviruses consist of nucleic acids and proteins enclosed in a lipid bilayer, primarily spreading through airborne droplets and aerosols.
- There are significant gaps in our understanding of how these viruses interact with biological and artificial surfaces, which is crucial for improving infection control measures and preparing for future pandemics.
Article Abstract
Much of the science underpinning the global response to the COVID-19 pandemic lies in the soft matter domain. Coronaviruses are composite particles with a core of nucleic acids complexed to proteins surrounded by a protein-studded lipid bilayer shell. A dominant route for transmission is via air-borne aerosols and droplets. Viral interaction with polymeric body fluids, particularly mucus, and cell membranes controls their infectivity, while their interaction with skin and artificial surfaces underpins cleaning and disinfection and the efficacy of masks and other personal protective equipment. The global response to COVID-19 has highlighted gaps in the soft matter knowledge base. We survey these gaps, especially as pertaining to the transmission of the disease, and suggest questions that can (and need to) be tackled, both in response to COVID-19 and to better prepare for future viral pandemics.
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| http://dx.doi.org/10.1039/d0sm01223h | DOI Listing |
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