Obtaining and Investigation of the -Cyclodextrin Inclusion Complex with Vitamin Oil Solution.

. The research results of fat-soluble vitamin (cholecalciferol) encapsulation with -cyclodextrin have been presented in this work. The vitamin inclusion complex with -cyclodextrin was obtained under microwave radiation. The surface morphology of obtained clathrate inclusion complexes was described with the help of a scanning electron microscope. The thermographic measurement results on a differential scanning calorimeter have been presented. The activation energy of the -cyclodextrin : vitamin clathrate complex thermal oxidative destruction reaction was calculated. The clathrate thermal destruction kinetic parameters were determined. The inclusion complex spectral properties were characterized by IR-Fourier and H and C NMR spectroscopy. The existence of -cyclodextrin inclusion complex with vitamin in a 2 : 1 ratio was confirmed by the experimental results. The activation energy of thermal destruction of the inclusion complex of -cyclodextrin with vitamin was calculated using four different methods.