We demonstrate experimentally the ability to use a single-pixel detector for two-dimensional high-resolution x-ray imaging of fast dynamics. We image the rotation of a spinning chopper at 100 kHz and at spatial resolution of about 40 microns by using the computational ghost imaging approach. The technique we develop can be used for the imaging of fast dynamics of periodic and periodically stimulated effects with a large field of view and at low dose.
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http://dx.doi.org/10.1364/OE.396497 | DOI Listing |
Fluids Barriers CNS
January 2025
Medical Image Processing Department, CHU Amiens-Picardie University Hospital, Amiens, France.
Background: The pressure gradient between the ventricles and the subarachnoid space (transmantle pressure) is crucial for understanding CSF circulation and the pathogenesis of certain neurodegenerative diseases. This pressure can be approximated by the pressure difference across the aqueduct (ΔP). Currently, no dedicated platform exists for quantifying ΔP, and no research has been conducted on the impact of breathing on ΔP.
View Article and Find Full Text PDFZoological Lett
January 2025
National Institutes of Natural Sciences, Exploratory Research Center On Life and Living Systems (ExCELLS), National Institute for Basic Biology, Okazaki, Aichi, 444-8787, Japan.
In vertebrates, skeletal muscle comprises fast and slow fibers. Slow and fast muscle cells in fish are spatially segregated; slow muscle cells are located only in a superficial region, and comprise a small fraction of the total muscle cell mass. Slow muscles support low-speed, low-force movements, while fast muscles are responsible for high-speed, high-force movements.
View Article and Find Full Text PDFNeuroimage
January 2025
Dept. of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA, USA.
A fast BEM (boundary element method) based approach is developed to solve an EEG/MEG forward problem for a modern high-resolution head model. The method utilizes a charge-based BEM accelerated by the fast multipole method (BEM-FMM) with an adaptive mesh pre-refinement method (called b-refinement) close to the singular dipole source(s). No costly matrix-filling or direct solution steps typical for the standard BEM are required; the method generates on-skin voltages as well as MEG magnetic fields for high-resolution head models within 90 seconds after initial model assembly using a regular workstation.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
IMoPA, UMR 7365, CNRS-Université de Lorraine, Nancy, France.
Background: While Alzheimer Disease (AD) patients' difficulty to recognize face identity (Werheid & Clare, 2007) has been mainly attributed to episodic and semantic memory impairments, these patients can also show abnormal difficulties at matching of unfamiliar faces for their identity, suggesting impaired perceptual function (Lavallée et al., 2016). However, since this latter evidence is based on explicit behavioural measures, the difficulties of AD patients can be due to many factors (e.
View Article and Find Full Text PDFBackground: Neuromodulatory subcortical systems (NSS) are affected from the early stages of Alzheimer's Disease (AD) by the accumulation of tau pathology. Increased tau burden within the subcortical nucleus that are in control of sleep and wake regulation may contribute to the breakdown of sleep-wake patterns in AD. A recent postmortem study showed that subcortical wake-promoting neurons were related to sleep phenotypes in AD and PSP, being that greater neuronal count in locus coeruleus (LC), tuberomammillary nucleus (TMN), and lateral hypothalamic area (LHA) associated with a decreased sleep drive (Oh et al.
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