Nickel-catalyzed reductive cross-coupling reactions have emerged as powerful methods to join two electrophiles. These reactions have proven particularly useful for the coupling of -alkyl electrophiles to form stereogenic centers; however, the development of enantioselective variants remains challenging. In this Perspective, we summarize the progress that has been made toward Ni-catalyzed enantioselective reductive cross-coupling reactions.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470226 | PMC |
| http://dx.doi.org/10.1021/acscatal.0c01842 | DOI Listing |
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