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Incidental left paraaortic mass in a patient with gall bladder adenocarcinoma: A diagnostic challenge.
Radiol Case Rep
March 2025
Department of Pathology, Bir Hospital, Kathmandu, Nepal.
Incidental adrenal masses are frequently detected due to the extensive use of cross-sectional imaging, with about 3% to 7% of adults estimated to have them. Paragangliomas and pheochromocytomas (PPGL), rare tumors originating from paraganglia tissues, including the adrenal medulla, continue to be imaging mimics, necessitating a multimodal approach for accurate diagnosis. We report a case of 72-years male presenting with intermittent pain abdomen for the past 1 year.
View Article and Find Full Text PDFAssociations between hypothalamic-pituitary-adrenal (HPA) axis hormone levels, major depression features and antidepressant effects of ketamine.
J Affect Disord
December 2024
Experimental Therapeutics and Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA. Electronic address:
Background: Subanesthetic doses of (R,S)-ketamine (ketamine) have demonstrated rapid and robust antidepressant effects in individuals with depression. However, individual variability in response to ketamine exists, and current biomarkers of ketamine treatment response are not entirely understood. Preclinical evidence suggests a link between hypothalamic-pituitary-adrenal (HPA) axis activation, a determinant of the stress response system, and ketamine's efficacy in stressed mice exhibiting enhanced antidepressant responses.
View Article and Find Full Text PDFEvaluation of sleep health in children with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
J Clin Endocrinol Metab
November 2024
Division of Pediatric Endocrinology, University of Minnesota Medical School, Minneapolis, MN.
Article Synopsis
- The study investigates sleep health in children and adolescents with congenital adrenal hyperplasia (CAH) using wrist actigraphy and sleep questionnaires.
- It found that these children had poorer sleep duration, efficiency, and more awakenings compared to healthy peers, particularly related to hydrocortisone medication timing.
- The results indicate that sleep issues are significant for children with CAH, highlighting the need for attention in clinical practice and further research.
High Diagnostic Accuracy of Arterial Phase CT in Differentiating Pheochromocytoma in Good/Poor Washout Adrenal Masses.
J Endocr Soc
November 2024
Department of Endocrinology, Seth G.S Medical College & KEM Hospital, Mumbai, Maharashtra 4000012, India.
Introduction: Differentiating pheochromocytomas from other adrenal masses based on computed tomography (CT) characteristics remains challenging, particularly in lipid-poor lesions with variable washout patterns. This study evaluated CT features for distinguishing pheochromocytomas in good and poor washout subcohorts.
Methods: We prospectively analyzed 72 patients with unilateral lipid-poor adrenal masses.
Clinical and radiological features of atypical adrenal masses- a multicenter retrospective study.
J Clin Endocrinol Metab
November 2024
Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Context: The natural history and malignant potential of cases classified as atypical adrenal masses (AAMs) are unknown.
Objective: To describe the radiological characteristics and clinical outcomes of AAMs.
Design And Participants: A multicenter retrospective study.
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