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Oxytocin ameliorates lipopolysaccharide-induced acute orchitis model: interplay of oxidative stress and inflammatory pathways.
Front Pharmacol
January 2025
Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia.
Introduction: Lipopolysaccharide (LPS), a constituent of the outer membrane of Gram-negative bacteria, is a powerful inducer of systemic inflammation and has been extensively utilized in experimental models to simulate inflammatory responses and septic disorders. Recent research indicates that oxytocin (OXY), a neuropeptide typically linked to social bonding and reproductive functions, may influence inflammatory processes. This work examines the impact of OXY on LPS-induced testicular damage, aiming to elucidate its therapeutic potential in addressing inflammatory disorders and broadening the comprehension of its functions beyond conventional neuroendocrine roles.
View Article and Find Full Text PDF2D Van der Waals Sliding Ferroelectrics Toward Novel Electronic Devices.
Small
January 2025
Wuhan National High Magnetic Field Center and School of Physics, Huazhong University of Science and Technology, Wuhan, 430074, China.
Ferroelectric materials, celebrated for their switchable polarization, have undergone significant evolution since their early discovery in Rochelle salt. Initial challenges, including water solubility and brittleness, are overcome with the development of perovskite ferroelectrics, which enable the creation of stable, high-quality thin films suitable for semiconductor applications. As the demand for miniaturization in nanoelectronics has increased, research has shifted toward low-dimensional materials.
View Article and Find Full Text PDFThe Role of Innate Immunity in Healthy Aging Through Antimicrobial Peptides.
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Aging Research Group, Korea Food Research Institute, Wanju-gun, South Korea.
In a super-aging society, the increase in the elderly population is closely tied to a rise in infectious diseases due to factors such as weakened immune systems and decreased vaccine efficacy in older adults. Various opportunistic pathogens commonly encountered in everyday life can cause infections and diseases when an individual's immune defence is weakened due to aging. These factors underscore the importance of preventive measures against pathogenic infections and the aging of immune systems in the elderly.
View Article and Find Full Text PDFRace Against the Clock: Severe Acute Abdominal Pain With Disastrous Complications.
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Pulmonary, Critical Care and Sleep Medicine, University of New Mexico Hospitals, Albuquerque, USA.
Although a rare medical condition, gastric ischemia is a medical emergency and requires prompt recognition. Current literature review is scarce, with a primary focus on iatrogenic, surgical, and vascular etiologies. The cases discussed focus on hypoperfusion secondary to refractory shock as the etiology of gastric ischemia and, unfortunately, death.
View Article and Find Full Text PDFBody size prediction in scorpions: a phylogenetic comparative examination of linear measurements of individual body parts.
PeerJ
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Department of Zoology, University of Tartu, Tartu, Estonia.
Body size has always been the focus of several ecological studies due to its undeniable influence on other life-history traits. The conventional representation of body size in arthropods typically relies on linear measures, such as total body length, or the length of specific body parts that can be used to represent body size. While these measures offer simplicity over more complicated alternatives (.
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