We report the case of a 10-year-old girl with bullous Sweet syndrome, recalcitrant to high-dose systemic corticosteroids. Subsequent treatment with infliximab resulted in a rapid improvement in cutaneous lesions and systemic symptoms. Cutis laxa was noted in the healed skin. We propose early second-line treatment with infliximab in children with steroid-refractory Sweet syndrome.

Download full-text PDF

Source
http://dx.doi.org/10.1111/pde.14356DOI Listing

Publication Analysis

Top Keywords

sweet syndrome
12
bullous sweet
8
10-year-old girl
8
treatment infliximab
8
infliximab treatment
4
treatment recalcitrant
4
recalcitrant bullous
4
syndrome 10-year-old
4
girl report
4
report case
4

Similar Publications

Molecular Characteristics of Sweet Syndrome: A Systematic Review.

Exp Dermatol

December 2024

Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Sweet syndrome (SS), originally described as acute febrile neutrophilic dermatosis, is a rare inflammatory skin condition, considered the prototype of neutrophilic dermatoses. It is characterised by the sudden onset of well-defined tender papules, plaques and nodules often accompanied by fever, neutrophilia and elevated markers of inflammation. Several variants have been described both clinically and histopathologically.

View Article and Find Full Text PDF

Background: Modest weight and lipid changes have been observed in cabotegravir plus rilpivirine long-acting (CAB+RPV LA) Phase 3/3b studies. The SOLAR study included standardized evaluations of weight and metabolic changes in people living with HIV switching to CAB+RPV LA dosed every 2 months (Q2M) vs. continuing bictegravir/emtricitabine/tenofovir (BIC/FTC/TAF).

View Article and Find Full Text PDF

Decitabine-induced Sweet syndrome.

BMJ Case Rep

December 2024

Pharmacy Practice, JSS College of Pharmacy, Mysuru, Karnataka, India

Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is a rare inflammatory skin condition associated with the sudden onset of high-grade fever, painful rashes usually on the upper body, leukocytosis and neutrophilia. Approximately 21% of patients with Sweet syndrome have a concurrent malignancy, 80% of which are linked to haematological diseases, especially myelodysplastic syndrome and acute myeloid leukaemia. This is a case report of a woman in her 50s who was recently diagnosed with acute myeloid leukaemia and was started on decitabine 20 mg/m (40 mg).

View Article and Find Full Text PDF

Sweet Syndrome Mimicking Flagellate Dermatitis.

Indian J Dermatol

October 2024

Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubiran", Mexico City, México.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!