Objective: to evaluate the use of realistic simulation as a strategy to promote teaching about pressure injuries.
Method: This is a quasi-experimental study. A modified and translated version of the Pieper Pressure Ulcer knowledge test was applied. Kappa statistical analysis was used to assess the professionals' knowledge in the realistic simulation using the SPSS software. A p-value <0.05 was considered significant.
Results: Seventy-seven nursing professionals participated in the realistic simulation, the majority (72.7%) being nursing technicians. Regarding the knowledge of primary and secondary coverage techniques, the Kappa index went from 0.56 (p=0.002) in the pre-test to 0.87 (p=0.001) in the post-test. As for the sterile dressing technique, there was a variation from 0.55 (p=0.002) in the pre-test to 0.91 (p=0.001) in the post-test. Regarding the cleaning of pressure injuries, there was a variation from 0.81 (CI: 0.62-0.84) in the pre-test to 0.91 (0.85-0.97) in the post-test. The knowledge about the use of a sterile spatula to distribute the dressing in the wound increased from an agreement index from regular to good.
Conclusion: The introduction of the realistic simulation in the clinical practice has created quality assessment indicators for the prevention and treatment of pressure injuries.
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http://dx.doi.org/10.1590/1518-8345.3946.3357 | DOI Listing |
J Blood Med
January 2025
Department of Blood Transfusion of Yong-chuan Hospital, Chongqing Medical University, Chongqing, 402160, People's Republic of China.
Purpose: To study the platelet adhesion and aggregation behaviour of late pregnancy women under arterial shear rate using microfluidic chip technology and evaluate the risk of thrombosis in late pregnancy.
Methods: We included pregnant women who were registered in the obstetrics department of our hospital between January 2021 and October 2022 and underwent regular prenatal examinations. Blood samples were collected at 32-35 weeks of gestation for routine blood tests and progesterone, oestradiol, and platelet aggregation function.
Brain Spine
December 2024
Department of Neurosurgery, University Hospital of Lausanne and University of Lausanne, 1011, Lausanne, Switzerland.
Introduction: While cadaveric dissections remain the cornerstone of education in skull base surgery, they are associated with high costs, difficulty acquiring specimens, and a lack of pathology in anatomical samples. This study evaluated the impact of a hand-crafted three-dimensional (3D)-printed head model and virtual reality (VR) in enhancing skull base surgery training.
Research Question: How effective are 3D-printed models and VR in enhancing training in skull base surgery?
Materials And Methods: A two-day skull base training course was conducted with 12 neurosurgical trainees and 11 faculty members.
Open Res Eur
January 2025
Universidad Politecnica de Madrid Departamento de Ingenieria Geologica y Minera, Madrid, Community of Madrid, 28003, Spain.
Background: This work was carried out within the framework of the SisAl Pilot project, which is devoted to the environmentally friendly production of silicon. This new method relies on the aluminothermic reduction of quartz in slag, offering a more sustainable alternative to the traditional reduction of silica with carbon in submerged arc furnaces.
Methods: The process takes place in a rotary kiln producing silicon (Si) and alumina slag (actually, a CaO - Al O slag), which must be separated at the end to extract the silicon.
J Control Release
January 2025
Dipartimento di Scienza dei Materiali, Università degli Studi di Milano-Bicocca, via R. Cozzi 55, 20125 Milano, Italy; BioNanoMedicine Center NANOMIB, Università degli Studi di Milano-Bicocca, Italy. Electronic address:
Graphene oxide (GO) is an amphiphilic and versatile graphene-based nanomaterial that is extremely promising for targeted drug delivery, which aims to administer drugs in a spatially and temporally controlled manner. A typical GO nanocarrier features a polyethylene glycol coating and conjugation to an active targeting ligand. However, it is challenging to accurately model GO dots, because of their intrinsically complex and not unique structure.
View Article and Find Full Text PDFInt J Pharm
January 2025
School of Mechanical and Mechatronic Engineering, University of Technology Sydney (UTS), 15 Broadway, Ultimo, New South Wales 2007, Australia. Electronic address:
Nanocarrier-based dry powders for lung disease treatment are crucial, with in vitro and in silico research being pivotal to their success. This study introduces a method for creating Tiotropium-bromide liposomal inhalation dry powder, termed "Trojan-particles," utilizing thin-film hydration and spray-drying with lactose-arginine carriers. Encapsulating tiotropium-bromide in nanoliposomes enhances lung treatment via liposomes' unique features.
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