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Chronobiological Patterns and Risk of Acute Aortic Dissection: A Clinical Retrospective and Two-Sample Mendelian Randomisation Study.
Heart Lung Circ
December 2024
Department of Cardiovascular Surgery, Changhai Hospital, Shanghai, China. Electronic address:
Aim: Acute aortic dissection (AAD) represents a cardiovascular ailment characterised by a notable mortality rate. Chronobiological patterns can offer a predictive framework for anticipating the onset of AAD.
Method: Data were gathered from 1,151 patients diagnosed with AAD at Changhai Hospital in Shanghai, China, spanning 2000-2023.
[DNA Methylation Profiling in Aneurysm and Comorbid Atherosclerosis of the Ascending Aorta].
Mol Biol (Mosk)
December 2024
Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, 634050 Russia.
Atherosclerosis and aneurysm of the aorta are relatively common pathological conditions that remain asymptomatic for a long period of time and have life-threatening and disabling complications. DNA methylation profiling in several regions (a dilated area, a nondilated area, and an atherosclerotic plaque) of the ascending aorta was carried out in patients with aortic aneurysm. DNA methylation was analyzed by reduced representation bisulfite sequencing (RRBS).
View Article and Find Full Text PDFValve-sparing procedure for acute aortic regurgitation due to intimal intussusception in a minimally localized aortic root dissection.
Gen Thorac Cardiovasc Surg Cases
December 2024
Department of Cardiovascular Surgery, National Center for Global Health and Medicine, Toyama 1-21-1, Shinjuku, Tokyo, Japan.
Background: Acute heart failure due to aortic regurgitation (AR) is a severe comorbidity of type A acute aortic dissection (AAD). Valve-sparing aortic root replacement is typically performed when the aortic valve remains intact.
Case Presentation: A 33-year-old male presented to our hospital with chest pain.
Long-term outcomes in thoracic aortic surgery: 11 year single centre experience.
J Cardiothorac Surg
December 2024
Department of Cardiac Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Objectives: Thoracic aortic aneurysms and dissections provide a complex surgical cohort termed thoracic aortic surgery. Regular follow-up at specialist clinics with cross-sectional imaging is recommended. Identifying risk factors that lead to re-operations as well as the requirement for and appropriate length of follow-up remain points of debate.
View Article and Find Full Text PDFChronobiological variations of acute aortic dissection in a Northwest Chinese population.
J Cardiothorac Surg
December 2024
Heart and Panvascular Diseases Medicine Treatment Center, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830001, People's Republic of China.
Background: The prevalence of acute aortic dissection (AAD) has been gradually increasing in recent years. This study aimed to investigate the circadian variations of AAD onset in a northwest Chinese population and provide scientific insights for AAD prevention.
Methods: The clinical data of 1,145 AAD patients admitted to our hospital between January 2010 and December 2020 were retrospectively collected, and the periodic features of AAD were analyzed.
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