Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00277-020-04248-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Coexistence of MYC/BCL2 double-hit of t(8;14)(q24;q32) and t(14;18)(q32;q21) and that of t(8;22)(q24;q11) and t(14;18) in advanced-stage high-grade B cell lymphoma.
Ann Hematol
December 2021
Tenri Institute of Medical Research, Tenri Hospital, Tenri, Nara, 632-8552, Japan.
Establishment and characterization of a novel 'double-hit' follicular lymphoma cell line, FL-SJC.
J Cell Mol Med
July 2020
Affiliated Hospital of Jiangsu University, Zhenjiang, China.
About 5 per cent of follicular lymphoma (FL) cases are double-hit (DH) lymphomas. Double-hit follicular lymphoma (DHFL) cell lines can improve our understanding and drug development on FL. But there are only few DHFL cell lines.
View Article and Find Full Text PDFPrimary mediastinal large B cell lymphoma with coexisting aberrations of C-MYC and BCL-2: a case report and literature review.
Med Mol Morphol
June 2020
Department of Hematology, The First Affiliated Hospital of China Medical University, No.155, Nanjing North Street, Shenyang, 110001, Liaoning, People's Republic of China.
Primary mediastinal large B-cell lymphoma (PMLBCL) is an aggressive lymphoma characteristic with distinct clinical, morphologic, and immunophenotypic features. The rearrangements of C-MYC, BCL2 and/or BCL6 which are common in diffuse large B-cell lymphoma (DLBCL) are typically absent in PLMBCL. Here we proved a novel case of PMLBCL with concurrent rearrangements of C-MYC and BCL2.
View Article and Find Full Text PDFB-cell lymphomas with concurrent MYC and BCL2 abnormalities other than translocations behave similarly to MYC/BCL2 double-hit lymphomas.
Mod Pathol
February 2015
Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Large B-cell lymphomas with IGH@BCL2 and MYC rearrangement, known as double-hit lymphoma (DHL), are clinically aggressive neoplasms with a poor prognosis. Some large B-cell lymphomas have concurrent abnormalities of MYC and BCL2 other than coexistent translocations. Little is known about patients with these lymphomas designated here as atypical DHL.
View Article and Find Full Text PDFCoexistent rearrangements of c-MYC, BCL2, and BCL6 genes in a diffuse large B-cell lymphoma.
Int J Hematol
January 2004
Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
We present a patient with stage III de novo diffuse large B-cell lymphoma. The lymphoma cells showed mature B-cell immunophenotype but lacked surface immunoglobulin (Ig) expression. Long-distance and long-distance inverse polymerase chain reaction assays to detect the oncogene/Ig gene rearrangement revealed that the cells carried 3 independent fusion genes, namely, c-MYC/Ig heavy chain gene (IgH), BCL2/IgH, and Ig lambda light chain gene/BCL6.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!