Carcinoids have been classified according to their embryonic origin in the past and are now categorized and classified as neuroendocrine tumors, including low malignant typical carcinoids, moderate malignant atypical carcinoids, and highly malignant large cell neuroendocrine and small cell carcinomas. A typical carcinoid is a previously used term for the current designation of a grade I neuroendocrine tumor, well differentiated, belonging to a group of rare tumors with a good prognosis with metastasis of less than 15% with a five-year survival of more than 90%, rarely producing serotonin. Even this bio-logically favorable tumor with a relatively low degree of metastasis cannot be underestimated. Case: The following section summarizes the classification of neuroendocrine tumors, their dia-gnosis and treatment, and the second section presents a specific case of a patient with multiple metastases of an original lung carcinoid (histology at the time of surgery 2012, at the time of using this older version of neuroendocrine tumors) describing its further treatment. Conclusion: In well differentiated neuroendocrine tumors, there is a significant risk of metastasis despite their radical surgery; their dispensarization is therefore necessary. The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study. The Editorial Board declares that the manuscript met the ICMJE recommendation for biomedical papers.
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http://dx.doi.org/10.14735/amko2020302 | DOI Listing |
S Afr J Surg
December 2024
Department of Surgery, School of Clinical Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, South Africa.
Background: Endocrine hypertension is believed to be underestimated worldwide especially in the developing countries. There is a scarcity of publications on endocrine hypertension in sub-Saharan Africa. The aim of this study was to reflect the profile of patients with endocrine hypertension of adrenal/paraganglioma origin at Chris Hani Baragwanath Academic Hospital (CHBAH).
View Article and Find Full Text PDFObjectives: Endoscopic ultrasonography (EUS)-guided radiofrequency ablation has recently been introduced as one of the management strategies for small pancreatic neuroendocrine neoplasms (PNENs). However, prospective data on its safety and efficacy remain limited.
Methods: This prospective pilot study was conducted at Okayama University Hospital from May 2023 to December 2024.
Sci Rep
January 2025
Key Laboratory of Cancer Immunotherapy of Guangdong Tertiary Education, Guangdong CAR-T Treatment Related Adverse Reaction Key Laboratory, The First Affiliated Hospital/Clinical Medical School, Guangdong Pharmaceutical University, Guangzhou, 510080, China.
Previously, we demonstrated that natural host-defence peptide caerin 1.1/caerin 1.9 (F1/F3) increases the efficacy of anti-PD-1 and therapeutic vaccine, in a HPV16 + TC-1 tumour model, but the anti-tumor mechanism of F1/F3 is still unclear.
View Article and Find Full Text PDFJ Nucl Med
January 2025
Orano Med LLC, Plano, Texas.
There are numerous versions of octreotide and octreotate, including DOTAMTATE, DOTATATE, JR11, and lead-specific chelator (PSC)-PEG2-TOC. These peptides, which can be either analogs or antagonists, are used in nuclear medicine for diagnostic imaging or targeted radionuclide therapy of neuroendocrine tumors that are positive for somatostatin receptors (SSTRs). Despite their structural and targeting similarities, they have distinct properties and clinical uses.
View Article and Find Full Text PDFNo Shinkei Geka
January 2025
Department of Neurosurgery, Osaka Metropolitan University Graduate School of Medicine.
Spinal extramedullary tumors are the most common types of schwannomas and meningiomas. Therefore, most spinal cord surgeons should safely perform surgeries for these tumors. The posterior approach with conventional laminectomy is sufficient for the safe resection of almost all spinal extramedullary tumors.
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