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A Case of Saddle Nose Deformity Secondary to Lepromatous Leprosy.
Indian J Otolaryngol Head Neck Surg
February 2025
Department of Pharmacology, Mamata Academy of Medical Sciences, Hyderabad, 500090 Telangana India.
Background: Leprosy is a chronic infectious disease caused by the Mycobacterium leprae affecting most commonly skin and peripheral nerves. Patients with Lepromatous Leprosy remain asymptomatic for years, and harbor bacteria in the nasal cavity, and these patients are responsible for the transmission of the disease in the community. In the advanced stage (stages 4 and 5) the involvement of nasal septum results in saddle nose deformity in most patients.
View Article and Find Full Text PDFOur patient presented with a 5-year history of chronic, asymptomatic papulonodular lesions on the extremities. The lesions spread to the face and earlobes, with new ulcerative lesions on both legs for the past 8 months. Skin biopsy was compatible with lepromatous leprosy with Lucio phenomenon.
View Article and Find Full Text PDFNecrotic erythema nodosum leprosum - A case of severe lepromatous reaction in a multibacillary leprosy patient.
IDCases
January 2025
Department of Internal Medicine, Rama Medical College Hospital and Research Center, Hapur, Uttar Pradesh, India.
Necrotic erythema nodosum leprosum (ENL) is an uncommon and severe complication of multibacillary leprosy, characterized by intense systemic inflammation, ulcerative lesions, and significant morbidity. This case report describes a 32-year-old male presenting with recurrent type 2 lepra reactions and necrotic lesions exacerbated by inconsistent adherence to multidrug therapy (MDT). The patient's management involved MDT, corticosteroids, thalidomide, and hydroxychloroquine, which led to a substantial clinical improvement.
View Article and Find Full Text PDFA Case of Lepromatous Leprosy Presenting With Multiple Morphologies in Philadelphia.
Cureus
December 2024
Dermatology, Temple University Hospital, Philadelphia, USA.
Leprosy is an uncommon chronic mycobacterial infection in the United States caused by . There are two major forms of the infection, lepromatous leprosy and tuberculoid leprosy, with borderline forms of each. Leprosy is even more uncommon in the Northeastern United States and can present with various symptoms and skin findings, including erythematous or hypopigmented patches or plaques with accompanying hypoesthesia or anesthesia, anhidrosis, or alopecia.
View Article and Find Full Text PDFPerforating ENL: A variant of type 2 lepra reaction.
J Clin Tuberc Other Mycobact Dis
February 2025
Department of Dermatology, Venereology and Leprosy, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.
Lepra reactions are acute episodic inflammatory reactions that occur during illness due to abrupt changes in the body's immunological response against Mycobacterium leprae. These are of two types, type 1 and type 2. Type 2 reaction is also called Erythema Nodosum Leprosum (ENL).
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