Measuring quality of life (QOL) after head and neck cancer (HNC), is rapidly becoming the standard of care. The Head and Neck Database Listing Evidence on QOL (Handle-On-QOL) is a dedicated QOL resource that includes articles published from 1982 onwards. The aim of this study was to assess the completeness of Handle-On-QOL, when compared with other non-specific search engines. Six years were selected at random; 1982, 1990, 1998, 2003, 2006, 2016. Four search engines were used (Medline, EMBASE, CINAHL, PsycINFO). Reporting followed PRISMA methodology. A total of 595 papers were assessed, of which 200 met the inclusion criteria. 186 papers were present on Handle-On-QOL, 243 were found on Handle-On-QOL for these six years, but not identified in the other searches, and 14 were missing from Handle-On-QOL. A search using standard engines generated a large number of irrelevant papers. Handle-On-QOL provides a comprehensive and accurate reflection of articles published using questionnaires to report QOL following HNC. This web-based repository (http://www.handle-on-qol.com) acts as a quick reference point for clinicians and researchers.
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http://dx.doi.org/10.1016/j.bjoms.2020.05.013 | DOI Listing |
J Appl Oral Sci
January 2025
Nanjing University, Research Institute of Stomatology, Affiliated Hospital of Medical School, Nanjing Stomatological Hospital, Department of Oral and Maxillofacial Trauma Orthognathic Plastic Surgery, Nanjing, China.
Objectives: Depth of invasion (DOI) in oral squamous cell carcinoma (OSCC) guides treatment and prognosis but lacks three-dimensional (3D) insight. Thus, this study aimed to investigate the feasibility and accuracy of Lugol's iodine-enhanced micro-computed tomography (CT) for the 3D measurement of DOI in OSCC samples.
Methodology: In total, 50 in vitro OSCC samples from Nanjing Stomatological Hospital (July 2022 to January 2024) were subjected to micro-CT imaging with a slice thickness of 50 μm following 3% Lugol iodine staining for 12 h, followed by pathological examination and staining.
J Craniofac Surg
January 2025
Department of Oral and Maxillofacial & Head and Neck Oncology, Capital Medical University School of Stomatology, Beijing, China.
Objective: This study aimed to compare the biomechanics of implant prostheses and peri-implant bone among 6 different mandibular reconstruction models based on patient data involving the use of an upper free-end double-barrel fibula.
Methods: This study was an observational study. Five models were reconstructed using fibular-supported and implant-supported partial dentures.
PLoS Pathog
January 2025
Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America.
Typical epidermodysplasia verruciformis (EV) is a rare, autosomal recessive disorder characterized by an unusual susceptibility to infection with specific skin-trophic types of human papillomavirus, principally betapapillomaviruses, and a propensity for developing malignant skin tumors in sun exposed regions. Its etiology reflects biallelic loss-of-function mutations in TMC6 (EVER1), TMC8 (EVER2) or CIB1. A TMC6-TMC8-CIB1 protein complex in the endoplasmic reticulum is hypothesized to be a restriction factor in keratinocytes for βHPV infection.
View Article and Find Full Text PDFActa Oncol
January 2025
Department of Oncology, Oslo University Hospital, Norway.
Background And Purpose: To present the clinical outcomes of two series of patients treated with carbon-ion radiotherapy (CIRT) and definitive photon radiotherapy (RT) for adenoid cystic carcinoma of the head and neck (HN-ACC).
Material And Methods: The first cohort of six patients was referred from Oslo University Hospital (OUS) to Centro Nazionale di Adroterapia Oncologica (CNAO, Pavia, Italy) for CIRT in 2014-2017. The second cohort included 18 patients treated with definitive photon RT at OUS in 2005-2017.
Cell Biochem Biophys
January 2025
Department of Otolaryngology, Head and Neck Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Sensorineural hearing loss (SNHL) is an increasingly prevalent sensory disorder, but the underlying mechanisms remain poorly understood. Adaptor related protein complex 2 subunit beta 1 (AP2B1) has been indicated to be detectable in mature cochleae. Nonetheless, it is unclear whether AP2B1 is implicated in the progression of SNHL.
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