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Health impacts of a remotely delivered prolonged nightly fasting intervention in stressed adults with memory decline and obesity: A nationwide randomized controlled pilot trial.
J Clin Transl Sci
November 2024
College of Health Solutions, Arizona State University, Phoenix, AZ, USA.
Objective/goals: Cognitive decline is intricately linked to various factors such as obesity, stress, poor sleep, and circadian rhythm misalignment, which are interrelated in their impact on cognitive health. Irregular food-intake timing further compounds these issues. The practice of prolonged nightly fasting (PNF) may help synchronize food intake with circadian rhythms, potentially mitigating adverse effects of cognitive decline and associated factors.
View Article and Find Full Text PDFManaging sleep issues in Parkinson's disease: an up-to-date review.
Expert Rev Neurother
January 2025
Department of Neurology, Dokkyo Medical University, Mibu, Japan.
Introduction: In Parkinson's disease (PD), sleep-wake problems are disease-related symptoms that occur throughout the day and have a negative impact on patients' quality of life to an extent that is equal to or greater than that of typical motor symptoms.
Areas Covered: Insomnia due to fragmented sleep and excessive daytime sleepiness (EDS) worsen as PD progresses. Nighttime wearing-off and early morning-off should be considered first when fragmented sleep is reported in PD patients.
A comparison of respiratory event-related electroencephalographic activity in obstructive sleep apnea alone co-morbid insomnia and sleep apnea (COMISA).
Eur Respir J
January 2025
Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada
Does six months of structured group exercise improve physical activity, sedentary behavior, and sleep in people living with dementia? A pilot randomized controlled trial.
Alzheimers Dement
December 2024
Augusta University, Augusta, GA, USA
Background: People living with dementia (PWD) often have inactivity‐induced muscle atrophy, increased sedentary behavior, and circadian rhythm disorders. Exercise may improve physical activity, sedentary behavior, and sleep in PWD, but further research is needed. The purpose of this pilot randomized controlled trial (RCT) was to examine whether a structured exercise program improves physical activity, sedentary behavior, and sleep in PWD.
View Article and Find Full Text PDFReevaluating Melatonin’s Efficacy in Alzheimer’s Disease: A 20th‐Anniversary Updated Literature Review of Sleep Disturbances and Treatment Trials.
Alzheimers Dement
December 2024
Northern Light Health, Bangor, ME, USA
Sleep disturbances in Alzheimer’s disease (AD) are stressful for patients and families. This review provides an update on the efficacy of melatonin and other interventions for nighttime sleep disturbances in AD patients, building on the original Alzheimer’s disease Cooperative Study trial, the first large trial for sleep disturbance in AD. The initial multicenter, randomized, placebo‐controlled study investigated the effects of two melatonin formulations – 2.
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