The morphological transformations that occur during adolescence with rapid rhythm have an unprecedented psychological resonance and it is of fundamental importance to understand the way in which they are lived, perceived and elaborated.These fast body changes and the related social pressures make young people paying more attention to their physical appearance. Among the changes that the adolescent must face are: accepting their own body, acquiring a social role, establishing new relationships with peers,achieving emotional independence from parents. All of this is not always easy and many times they face a so difficult path that can produce the onset of some mental pathologies. Typical disorders that adolescents can face are the ones related to food. In these pathologies there is an isolation of the soul which corresponds to an alienation from the body: what remains in this loneliness is the gap between the idealized body and the objectified body. In this process of identity determination the idealized body is not able to relate to the real body (Cuzzolaro 2017). The dimension of their own body and the ability to meet the other bodies in the world are compromised; the only possible knowledge is represented by the impoverishment of their own subjectivity and by the attempt to recover it at an abstract level. Adolescents live in a condition of temporal suspension: the future is compromised and the past is demonized; what remains is a present moment made eternal by an indefinitely suspended instant (Juli 2018). Too fat for the anorexic, repulsive for binge eating; Merleau-Ponty already in 1945 expressed the concept of corporeality by using the following simple and very effective statement: "I am my body". This statement highlights the centrality of the body, of the person and his/her identity; this aspects are highly conflicting and, at the same time, pathologically united, in eating disorders.
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Magn Reson Med
January 2025
F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.
Purpose: We hypothesized that radiation-induced tubulointerstitial changes in the kidney can be assessed using MRI-based T relaxation time measurements.
Methods: We performed MRI, histology, and serum biochemistry in two mouse models of radiation nephropathy: one involving external beam radiotherapy and the other using internal irradiation with an α-particle-emitting actinium-225 radiolabeled antibody. We compared the mean T values of different renal compartments between control and external beam radiotherapy or α-particle-emitting actinium-225 radiolabeled antibody-treated groups and between the two radiation-treated groups using a Wilcoxon rank-sum test.
Biomol Concepts
January 2025
Division of Pharmacology, School of Medical and Life Sciences, Sunway University, No. 5, Jalan Universiti, Bandar Sunway, 47500 Selangor Darul Ehsan, Malaysia.
Seaweeds have been utilized as food, fodder, fertilizer, and medicine since ancient times; nevertheless, they have received only a little attention. In the current work, we extracted the sulfated polysaccharide from a marine source and investigated its anti-arthritic potential . The isolated and freeze-dried polysaccharide was tested for acute oral toxicity based on OECD 423.
View Article and Find Full Text PDFZool Res
January 2025
Institute of Brain Science and Disease, School of Basic Medicine, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, Qingdao University, Qingdao, Shandong 266071, China. E-mail:
Substantial evidence points to the early onset of peripheral inflammation in the development of Parkinson's disease (PD), supporting the "body-first" hypothesis. However, there remains a notable absence of PD-specific animal models induced by inflammatory cytokines. This study introduces a novel mouse model of PD driven by the proinflammatory cytokine CXCL1, identified in our previous research.
View Article and Find Full Text PDFJ Forensic Sci
January 2025
Department of Entomology, Texas A&M University, College Station, Texas, USA.
The house fly, Musca domestica, L. (Diptera: Muscidae), is a filth fly that is often associated with criminal and civil investigations surrounding abuse, neglect, and death of humans and other vertebrates. However, development data, which are crucial for determining the age of immatures collected under forensically relevant circumstances, are limited.
View Article and Find Full Text PDFRev Med Suisse
January 2025
Service d'oncologie, Hôpitaux universitaires de Genève, 1211 Genève 14.
New therapeutic agents in oncology are emerging rapidly, both in terms of the number of approved drugs and the technological and biological innovation of new treatments. Antibody-drug conjugates (ADC) offer a promising cancer therapy by specifically targeting tumor cells. ADC are composed of a monoclonal antibody recognizing the tumor cell via specific antigens, coupled with a potent cytotoxic agent that resembles classical chemotherapy.
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