Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Estrogen-mediated modulation of sterile inflammatory markers and baroreflex sensitivity in ovariectomized female Wistar rats.
Arch Endocrinol Metab
January 2025
Jamia Hamdard School of Chemical & Life Sciences Department of Biotechnology New Delhi India Department of Biotechnology, School of Chemical & Life Sciences, Jamia Hamdard, New Delhi.
Objective: This study aims to explore the role of estrogen in providing cardioprotective benefits to premenopausal women, examining how hormonal differences between sexes influence the prevalence of cardiovascular diseases (CVDs) in women.
Materials And Methods: Eighteen female Wistar rats were equally distributed into three treatment groups. Animals in Group I (sham-operated) and Group II (ovariectomized [OVX]) received oral saline solution at a dose of 2 mL/kg.
'I wish I had been better prepared': a mixed-methods study of psychological reactions, perceptions and opinions of cardiovascular preparticipation screening among young competitive athletes.
Br J Sports Med
January 2025
Department of Medicine, Queen's University, Kingston, Ontario, Canada.
Objective: To evaluate the psychological reactions, perceptions and opinions of cardiovascular preparticipation screening (PPS) among young competitive athletes.
Methods: This convergent parallel mixed-methods study recruited 222 athletes (mean age: 18.7 years) who underwent PPS at a Canadian university.
Abnormal cardiovascular control during exercise: Role of insulin resistance in the brain.
Auton Neurosci
January 2025
Departments of Applied Clinical Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:
During exercise circulatory adjustments to meet oxygen demands are mediated by multiple autonomic mechanisms, the skeletal muscle exercise pressor reflex (EPR), the baroreflex (BR), and by feedforward signals from central command neurons in higher brain centers. Insulin resistance in peripheral tissues includes sensitization of skeletal muscle afferents by hyperinsulinemia which is in part responsible for the abnormally heightened EPR function observed in diabetic animal models and patients. However, the role of insulin signaling within the central nervous system (CNS) is receiving increased attention as a potential therapeutic intervention in diseases with underlying insulin resistance.
View Article and Find Full Text PDFLong-Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model.
Adv Sci (Weinh)
January 2025
Department of Otolaryngology, Case Western Reserve University, Cleveland, OH, 44106, USA.
Usher syndrome type 1C (USH1C) is a genetic disorder caused by mutations in the USH1C gene, which encodes harmonin, a key component of the mechanoelectrical transduction complex in auditory and vestibular hair cells. USH1C leads to deafness and vestibular dysfunction in humans. An Ush1c knockout (KO) mouse model displaying these characteristic deficits is generated in our laboratory.
View Article and Find Full Text PDFCardioneuroablation in the Management of Vagally Mediated Bradyarrhythmias-A Comprehensive Review of Ongoing Randomized Controlled Trials.
J Clin Med
January 2025
Department of Cardiology, Center for Heart Diseases, 4th Military Hospital, 50-981 Wrocław, Poland.
Cardioneuroablation is a rapidly developing procedure for the treatment of vagally mediated bradyarrhythmias. However, the lack of multicenter, randomized trials prevents it from being included in bradyarrhythmia treatment guidelines. So far, only one small, randomized study has been published assessing the effectiveness of this method in the treatment of reflex syncope.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!