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Practical approach to the management of smoldering myeloma. | LitMetric

Practical approach to the management of smoldering myeloma.

Curr Opin Oncol

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia, USA.

Published: November 2020

AI Article Synopsis

  • The article reviews how to diagnose and assess risks associated with smoldering myeloma (SMM), focusing on practical management strategies for clinicians.
  • It discusses recent studies (ECOG E3A06 and GEM-CESAR) that highlight the benefits of early treatment for high-risk SMM patients, emphasizing the real-world implications of these findings.
  • The conclusions point out that the methods for risk assessment and standard treatment for SMM are changing, and the article offers updates on clinical data and management recommendations.

Article Abstract

Purpose Of Review: The aim of this article is to review the diagnosis and risk stratification of smoldering myeloma (SMM), describe recently published data regarding the early treatment of SMM, and to provide practical strategies on how to manage patients with SMM in the clinic.

Recent Findings: Recently published data from the ECOG E3A06 and GEM-CESAR studies supporting early intervention for certain subsets of high-risk SMM patients will be presented, and the relevance of these findings in relation to real-life application will be explored.

Summary: Accurate risk-stratification and standard of care for SMM is evolving, and here we summarize the pertinent clinical data and provide recommendations for clinical management of SMM patients.

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCO.0000000000000676DOI Listing

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