AI Article Synopsis
- Phenomic studies analyze how phenotypes, genotypes, and environmental factors interconnect, offering a broad understanding of biological systems.
- Yeast (Saccharomyces cerevisiae) serves as a key model organism in these studies because of its extensive range of genome-wide strain collections.
- The text outlines a specific protocol for conducting a yeast phenomic screen to assess protein colocalization through a genome-wide imaging method that uses a collection of GFP-tagged yeast strains.
Article Abstract
Phenomic studies can provide a systemic overview of the network of interactions between phenotypes, genotypes, and environmental factors. Yeast (Saccharomyces cerevisiae) is one of the most important model organisms for phenomic studies due to the availability of a large variety of genome-wide strain collections. We describe a detailed protocol for performing a yeast phenomic screen for evaluation of protein colocalization via a genome-wide imaging-based screening approach utilizing a GFP-tagged yeast strain collection.
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| http://dx.doi.org/10.1007/978-1-0716-0868-5_8 | DOI Listing |
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