AI Article Synopsis
- The study aimed to explore how different lighting levels impact reading performance in Japanese patients with age-related macular degeneration (AMD) and to identify the factors influencing this.
- A total of 39 AMD patients were tested on their reading abilities using Japanese sentences in varying light conditions (500-7500 lx), with a focus on those with and without central scotomas.
- Results showed that reading acuity improved notably at higher light levels, especially in patients without central scotomas, while critical print size and maximal reading speed did not show significant improvement across different light conditions.
Article Abstract
Purpose: Several studies of Western patients with age-related macular degeneration (AMD) have investigated reading performance that improved at high levels of illumination; however, the relation between reading performance and macular function has not been evaluated in detail in Japan. The goals of this study were to evaluate the effect of different levels of illumination on reading performance in Japanese patients with AMD and determine the factors, such as macular function, that affect these results.
Study Design: Cross-sectional study.
Methods: We prospectively included 39 patients with bilateral AMD or maculopathy. We evaluated reading performance; reading acuity (RA), critical print size (CPS), and maximal reading speed (MRS) using charts with Japanese sentences based on the MNREAD-J in 500-7500 lx. Patients were classified into two groups based on the presence of a central scotoma (CS) or no CS (NCS) diagnosed by microperimetry.
Results: The RA improved significantly in 500-7500 lx in both groups (NCS, p = 0.001; CS, p = 0.046). The RA improvement differed significantly (2000 lx, p = 0.021; 5,000 lx; p = 0.021; 7500 lx, p = 0.047) between 500 lx and other illumination levels only in the NCS group and then plateaued over 2000 lx. The CPS and MRS did not improve significantly at any illumination level.
Conclusions: These results suggest that the difference in macular function was related to improvement in the RA with increased illumination in Japanese patients with AMD.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10384-020-00769-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Characterization of mint virus C, a new member of the genus Carlavirus.
Arch Virol
January 2025
Institute for Sustainable Plant Protection, CNR, Strada delle Cacce 73, 10135, Torino, Italy.
Here, we report the complete genome sequence of a new carlavirus causing mosaic on mint plants in Italy, which we have tentatively named "mint virus C" (MVC). Flexuous particles of around 600 nm were observed using transmission electron microscopy, and next-generation sequencing was performed to determine the nucleotide sequence of the MVC genome, which was found to be 8558 nt long, excluding the poly(A) tail, and shows the typical organization of a carlavirus. The putative proteins encoded by MVC are 44-56% identical to the closest matches in the NCBI database, suggesting that MVC should be considered a member of a new species in the genus Carlavirus.
View Article and Find Full Text PDFPatient- and clinician-based evaluation of large language models for patient education in prostate cancer radiotherapy.
Strahlenther Onkol
January 2025
Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Background: This study aims to evaluate the capabilities and limitations of large language models (LLMs) for providing patient education for men undergoing radiotherapy for localized prostate cancer, incorporating assessments from both clinicians and patients.
Methods: Six questions about definitive radiotherapy for prostate cancer were designed based on common patient inquiries. These questions were presented to different LLMs [ChatGPT‑4, ChatGPT-4o (both OpenAI Inc.
Automated classification of coronary LEsions fRom coronary computed Tomography angiography scans with an updated deep learning model: ALERT study.
Eur Radiol
January 2025
Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.
Objectives: The use of deep learning models for quantitative measurements on coronary computed tomography angiography (CCTA) may reduce inter-reader variability and increase efficiency in clinical reporting. This study aimed to investigate the diagnostic performance of a recently updated deep learning model (CorEx-2.0) for quantifying coronary stenosis, compared separately with two expert CCTA readers as references.
View Article and Find Full Text PDFDevelopment of a Semiquantitative Barcode Readout Approach for Paper-Based Analytical Devices (PADs) for Enzymatic HO and Glucose Detection.
Anal Chem
January 2025
Department of Applied Chemistry, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
The integration of barcode technology with smartphones on paper-based analytical devices (PADs) presents a promising approach to bridging manual detection with digital interpretation and data storage. However, previous studies of 1D barcode approaches have been limited to providing only a "yes/no" response for analyte detection. Herein, a method of using barcode readout for semiquantitative signal detection on PADs has been achieved through the integration of barcode technology with a distance-based measurement concept on PADs.
View Article and Find Full Text PDFEnhancing Patient Comprehension of Glomerular Disease Treatments Using ChatGPT.
Healthcare (Basel)
December 2024
Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.
: It is often challenging for patients to understand treatment options, their mechanisms of action, and the potential side effects of each treatment option for glomerular disorders. This study explored the ability of ChatGPT to simplify these treatment options to enhance patient understanding. : GPT-4 was queried on sixty-seven glomerular disorders using two distinct queries for a general explanation and an explanation adjusted for an 8th grade level or lower.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!