Although a large panel of natural antioxidants demonstrate a protective effect in preventing cellular oxidative stress, their low bioavailability limits therapeutic activity at the targeted injury site. The importance to deliver drug or cells into oxidative microenvironments can be realized with the development of biocompatible redox-modulating materials. The incorporation of antioxidant compounds within implanted biomaterials should be able to retain the antioxidant activity, while also allowing graft survival and tissue recovery. This review summarizes the recent literature reporting the combined role of natural antioxidants with biomaterials. Our review highlights how such functionalization is a promising strategy in tissue engineering to improve the engraftment and promote tissue healing or regeneration.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552777 | PMC |
| http://dx.doi.org/10.3390/bioengineering7030104 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
From micro to macro, nanotechnology demystifies acute pancreatitis: a new generation of treatment options emerges.
J Nanobiotechnology
January 2025
Department of Gastroenterology, Shanghai Institute of Pancreatic Diseases, National Key Laboratory of Immunity and Inflammation, Changhai Hospital, Naval Medical University, Shanghai, 200433, China.
Acute pancreatitis (AP) is a disease characterized by an acute inflammatory response in the pancreas. This is caused by the abnormal activation of pancreatic enzymes by a variety of etiologic factors, which results in a localized inflammatory response. The symptoms of this disease include abdominal pain, nausea and vomiting and fever.
View Article and Find Full Text PDFUnexpected species diversity in the understanding of selenium-containing soil invertebrates.
Sci Rep
January 2025
Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization, Hubei Collaborative Innovation Center for the Characteristic Resources Exploitation of Dabie Mountains, College of Biology and Agricultural Resources, Hubei Zhongke Research Institute of Industrial Technology, Huanggang Normal University, Huanggang, 438000, Hubei, China.
Yutangba, situated in Enshi City, Hubei Province, is globally noted for its high selenium (Se) content. Soil invertebrates are essential to the functionality and services of terrestrial ecosystems, yet their community composition in this region remains under-explored. This study utilized environmental DNA metabarcoding to investigate the interrelations among environmental factors, soil invertebrate diversity, and community characteristics concerning soil Se content, pH, and moisture content in the region.
View Article and Find Full Text PDFChemoprevention Strategies for Precancerous Gastric Lesions Beyond Helicobacter pylori Eradication.
QJM
January 2025
Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan), Peking University Health Science Center, Beijing, 100091, People's Republic of China.
Gastric cancer (GC) is a significant global health challenge, particularly in high-incidence regions like East Asia. Despite improvements in screening and treatment, the progressive nature of precancerous lesions-such as atrophic gastritis, intestinal metaplasia, and dysplasia-necessitates effective prevention strategies. This review evaluates the role of chemoprevention in GC, focusing on agents designed to target these precancerous lesions.
View Article and Find Full Text PDFInfluence of chitosan encapsulation on functionality and stability of astaxanthin nanoemulsion fabricated using high pressure homogenizer.
Int J Biol Macromol
January 2025
Department of Food Technology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address:
Astaxanthin is a natural antioxidant substance, but it can be easily degraded by light, heat, and oxidation. One solution to overcome these problems is to transform astaxanthin into nanoemulsion within a protective matrix produced during an encapsulation process. In this study astaxanthin nanoemulsion (ANE) and chitosan (CS) incorporated with ANE (CS-ANE) were fabricated using high-pressure homogenizer (HPH).
View Article and Find Full Text PDFBaicalein antagonises Rhopilema esculentum toxin-induced oxidative stress and apoptosis by modulating ROS-MAPK-NF-κB and inhibiting PLA activity.
Toxicon
January 2025
College of Traditional Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. Electronic address:
The toxicity of jellyfish Rhopilema esculentum (R. esculentum), an edible jellyfish that releases venom, has been controversial. The aim of this comprehensive study was to investigate the toxic effects of jellyfish tentacle extract (TE), which was evaluated in vivo and in vitro using ICR mice and RAW264.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!