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Background: The CN-6000 (Sysmex Corp.) is a new haemostasis analyser with blood coagulation, amidolytic, immuno-turbidometric and light transmission aggregometry (LTA) capabilities. Transmitted light is monitored at multiple wavelengths (340, 405, 575, 660, 800 nm), from an LED light source.
Aims: To evaluate the performance of the CN-6000 against a predicate device.
Methods: The CN-6000 was evaluated against the CS-5100 (Sysmex) for 14 different tests, using 880 samples from normal subjects, anticoagulated patients, critically ill patients, plasmas with high or low fibrinogen content or abnormal levels of interfering substances. Between-day assay imprecision was assessed using commercial QC materials (n = 10 replicates on each of 5 days).
Results: Acceptable levels of imprecision were obtained for all assays. Agreement between the two analysers was excellent for all assays. Throughput was 35% higher using the CN-6000 (337 vs 250 tests per hour for PT, aPTT and fibrinogen). The CN-6000 also demonstrated improved clot detection in plasmas with high levels of interfering substances as demonstrated by a 29% reduction in "vote-outs" due to low light transmission (24 vs 34).
Conclusions: The CN-6000 demonstrated excellent comparability with the predicate instrument and acceptable levels of imprecision in all assays. Improvements in throughput and clot detection in the presence of interfering substances were also shown.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291559 | PMC |
http://dx.doi.org/10.1111/ijlh.13271 | DOI Listing |
Heliyon
December 2024
Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi, 6205, Bangladesh.
Global efforts have been made to address environmental and health concerns by promoting and adopting renewable natural resources. This study investigated the role of bagasse-based wood vinegar to synthesize and stabilize silver nanoparticles. We present a simple bottom-up approach to produce silver nanoparticles using the green reducing agent.
View Article and Find Full Text PDFWe experimentally demonstrate a cost-effective dual-polarization quadrature phase shift keying (DP-QPSK) coherent passive optical network (PON) system that operates at 100 Gbits/s/λ. This system utilizes distributed feedback lasers (DFBs) and a carrier recovery algorithm facilitated by a bifunctional frequency-domain pilot tone (FPT). To reduce costs in coherent PON implementations, low-cost DFBs are employed as the sole light sources, replacing the more expensive external cavity lasers (ECLs) at both the optical line terminal (OLT) and the optical network units (ONUs).
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
Institute of Materials for Electronics and Energy Technology (i-MEET), Department of Materials Science and Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg, Martensstrasse 7, Erlangen 91058, Germany.
In recent years, luminescent solar concentrators (LSCs) have gained a renaissance as a pivotal transparent photovoltaic (PV) for building-integrated photovoltaics (BIPVs). However, most of the studies focused on light-selective LSCs, and less attention was paid to the utilization of the full solar spectrum. In this study, a lead-free microcrystal CsAgNaBiInCl (CANBIC) perovskite phosphor is demonstrated to have bifunctional effects of luminescent down-shifting (LDS) and light scattering for the fabrication of LSCs, realizing light response from ultraviolet (UV) to NIR regions by an edge-mounted Si solar cell.
View Article and Find Full Text PDFJ Agric Food Chem
December 2024
Guangdong Province Key Laboratory of Microbial Signals and Disease Control, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China.
Rice stripe mosaic virus (RSMV) is the sole cytoplasmic rhabdovirus documented in naturally infected rice plants. It encodes P6, which induces delayed heading and reduces yield in infected rice plants. P6 of RSMV interacts with OsHAPL1, facilitating the interaction between OsHAPL1 and DTH8, resulting in delayed rice heading under long day conditions.
View Article and Find Full Text PDFHeliyon
December 2024
Chemistry Department, Faculty of Science, Cairo University, Giza, 12613, Egypt.
The extensive use of azo dyes in textile and pharmaceutical industries pose significant environmental and health risks. This problem requires to be tackled forthwith through a cheap, environmentally friendly and viable approach to mitigate water pollution. In this context, the green synthesis method was used for synthesis of ZnO NPs.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!