AI Article Synopsis

  • - The study highlights the challenges of assessing dementia prevalence in low- and middle-income countries (LMIC) due to limited data and inconsistencies in identifying dementia cases.
  • - Researchers used data from ten population aging surveys to analyze dementia likelihood and estimate prevalence, employing hierarchical clustering and principal component analysis.
  • - Their findings indicated significant dementia cases globally, estimating approximately 130 million individuals with dementia in 2015, with notably higher numbers in LMIC compared to high-income countries.

Article Abstract

Introduction: Ability to determine dementia prevalence in low- and middle-income countries (LMIC) remains challenging because of frequent lack of data and large discrepancies in dementia case ascertainment.

Methods: High likelihood of dementia was determined with hierarchical clustering after principal component analysis applied in 10 population surveys of aging: HRS (USA, 2014), SHARE (Europe and Israel, 2015), MHAS (Mexico, 2015), ELSI (Brazil, 2016), CHARLS (China, 2015), IFLS (Indonesia, 2014-2015), LASI (India, 2016), SAGE-Ghana (2007), SAGE-South Africa (2007), SAGE-Russia (2007-2010). We approximated dementia prevalence using weighting methods.

Results: Estimated numbers of dementia cases were: China, 40.2 million; India, 18.0 million; Russia, 5.2 million; Europe and Israel, 5.0 million; United States, 4.4 million; Brazil, 2.2 million; Mexico, 1.6 million; Indonesia, 1.3 million; South Africa, 1.0 million; Ghana, 319,000.

Discussion: Our estimations were similar to prior ones in high-income countries but much higher in LMIC. Extrapolating these results globally, we suggest that almost 130 million people worldwide were living with dementia in 2015.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453145PMC
http://dx.doi.org/10.1002/trc2.12074DOI Listing

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