Aim: This research aimed to investigate the differences in the sealing capability of propolis extracts and Ca(OH) on dentin surfaces.
Materials And Methods: Eighteen mandible incisors of Wistar rats were prepared at a depth of 0.5 mm after which they were randomly divided into 3 groups (n=6) including control (C), pulp-capped with Ca(OH) group (P1), and indirect pulp-capped with propolis extract group (P2). All the cavities were sealed with glass ionomer restorative cement. Moreover, the sections of the teeth were obtained after six Wistar Rats from each group were sacrificed on the second day after treatment. The rats' incisors were cleaved transversally to the area where Ca(OH) and propolis extract bonded with dentin for the SEM (scanning electron microscope) analysis and examined using microphotographs test with 5000x magnification. All the samples were measured and examined with spectrophotometry test to determine the bonding distance between Ca(OH) and dentin, as well as propolis extract and dentin. The result from the two tests was analyzed with SPSS using an independent -test at p <0.05.
Results: There were significant differences between the calcium hydroxide and propolis extract groups (p<0.05) based on the results obtained in the form of spectrums chemical functional groups of spectrophotometry examination. No new chemical bonding or compound was also observed to have been formed between propolis extract with dentin as well as calcium hydroxide with dentin.
Conclusion: The adaptation or sealing capability of propolis extract was found to be better than calcium hydroxide to the dentin surface.
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http://dx.doi.org/10.2147/CCIDE.S243714 | DOI Listing |
Heliyon
January 2025
Department of Restorative Dentistry and Endodontic, Faculty of Dentistry, Damascus University, Damascus, Syria.
Background: () is one of the microorganisms responsible for the pathology of root canals. We aimed in this study to determine the efficacy of two different pastes (calcium hydroxide combined with saline and calcium hydroxide combined with propolis) as a dressing material in eradicating from infected root canals.
Methods: Twenty extracted single-rooted and single-canalled first premolars randomly distributed into two equal groups of 10 teeth each.
Int J Biol Macromol
January 2025
Food Eng. Department, Chemical and Metallurgical Engineering Faculty, Yildiz Technical University, 34210 Istanbul, Turkiye. Electronic address:
Liposomes are gaining interest in food and pharmaceutical applications due to their biocompatibility and non-toxicity. However, they suffer from low colloidal stability, leakage of encapsulated substances, and poor resistance to intestinal digestive conditions. To address these issues, propolis extract (PE) was encapsulated within a hybrid system combining liposomes and hydrogels.
View Article and Find Full Text PDFBDJ Open
January 2025
Department of Orthodontics, Institute of Dentistry, Medical Faculty, Jagiellonian University, Kraków, Poland.
Background And Objectives: Gingivitis and periodontitis are common periodontal diseases that can significantly harm overall oral health, affecting the teeth and their supporting tissues, along with the surrounding anatomical structures, and if left untreated, leading to the total destruction of the alveolar bone and the connective tissues, tooth loss, and other more serious systemic health issues. Numerous studies have shown that propolis can help reduce gum inflammation, inhibit the growth of pathogenic bacteria, and promote tissue regeneration, but with varying degrees of success reported. For this reason, this comprehensive systematic review aims at finding out the truth concerning the efficacy of propolis mouthwashes in treating gingivitis and periodontitis, as its main objective.
View Article and Find Full Text PDFPharmaceuticals (Basel)
January 2025
MML Medical Centre, Bagno 2, 00-112 Warsaw, Poland.
Inappropriate and excessive use of antibiotics is responsible for the rapid development of antimicrobial resistance, which is associated with increased patient morbidity and mortality. There is an urgent need to explore new antibiotics or alternative antimicrobial agents. a commensal microorganism but is also responsible for numerous infections.
View Article and Find Full Text PDFPharmaceuticals (Basel)
January 2025
Department of Pharmaceutical Botany, Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaşi, Romania.
The present experiment aimed to formulate four ointments that included mixtures of plant extracts (, , , and ), apitherapy products (honey, propolis, and apilarnil) and natural polymers (collagen, chitosan, and the lyophilisate of egg white) in an ointment base. : In order to investigate the therapeutic properties of the ointments, experimental in vivo injury models (linear incision, circular excision, and thermal burns) were performed on laboratory animals, namely Wistar rats. The treatment was applied topically, once a day, for 21 days.
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